The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: May 5, 2025
Herein, we developed a methodology for the synthesis of 4H-3,1-benzoxazine derivatives by utilizing 2-azidobenzaldehydes and homoallylic alcohols in presence BF3·OEt2 moderate to good yields. This reaction proceeds via retro-Prins reaction, followed nucleophilic attack azide subsequent elimination nitrogen proton. In addition, method was successfully applied triazole compounds click reaction.
Language: Английский