Electrochemical N–H Methylsulfoxidation of Sulfoximines with DMSO

Chinese Journal of Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 16, 2025

Comprehensive Summary The N–H methylsulfoxidation of sulfoximines using DMSO as a methylsulfinyl source, induced by electrochemistry, has been developed. This method is the first example an electrochemical reaction in which serves source. Unlike previous reactions involving substrate, exclusively proceed via radical mechanisms, this follows S‐cation pathway. A wide range N ‐methylsulfinyl were successfully obtained.

Language: Английский

Strategies for oxidative synthesis of N-triflyl sulfoximines

RSC Advances, Journal Year: 2024, Volume and Issue: 14(42), P. 30836 - 30843

Published: Jan. 1, 2024

Using different oxidation systems, a large number of N -triflylsulfoximines have been synthesized, some which further functionalized.

Language: Английский

Advances in Cross and Oxidative Coupling Reactions of NH-Sulfoximines – A review

Chemical Communications, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 23, 2024

Due to the special structure and physicochemical properties of sulfoximines, research on sulfoximines has achieved great progress in recent decades, especially chemical medicinal fields. This review highlights advancements N-functionalization NH-sulfoximines, focusing classical cross-coupling reactions with electrophilic agents oxidative coupling extensive organic compounds, including specific (hetero)arenes, alkenes (1,4-naphthoquinones), alkanes (cyclohexanes), nucleophiles (thiols, disulfides, sulfinates, diarylphosphine oxides), organyl boronic acids, arylhydrazines. Transition metal-catalyzed, metal-free, electrochemical radical are discussed. also reports discusses mechanistic pathways some typical reactions.

Language: Английский