The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(21), P. 15686 - 15693
Published: Oct. 21, 2024
A unified method toward the synthesis of functionalized diazepines and quinazolines through reorganization molecular skeleton has been devised. The process is indulged by electrical energy via a domino N1–N2 bond cleavage followed concomitant ring closing, initiating from cinnolines indazoles as designed precursors. Additionally, an intermolecular homologation also established to synthesize densely dihydroquinazolines 2,3-diaryl-indazoles acetonitrile involving same electrochemical strategy.
Language: Английский