Nickel/Photoredox Dual-Catalyzed, Regioselective 1,2-Carboacylation of Alkenes via Synergistic Alkyl and Benzoyl Radical Coupling DOI

Xian‐Chen He,

Jie Gao, Yang Li

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: May 2, 2025

A regioselective 1,2-carboacylation protocol of alkenes via nickel/photoredox dual catalysis has been successfully developed under mild conditions. wide range alkyl bromides, α-oxocarboxylic acids, and styrenes proved to be compatible the optimized conditions, affording corresponding products in up 91% yields. Mechanistically, key success this approach is temporal orchestration radical generation: nickel-catalyzed halogen atom transfer (XAT) for bromides photoredox-driven decarboxylation acids.

Language: Английский

Photoredox Nickel-Catalyzed Radical Cyclization of N-Arylacrylamides with Alkyl Bromides DOI

Yanling Liu,

Lei Shi,

Xian‐Chen He

et al.

Organic & Biomolecular Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

We present a photoredox nickel-catalyzed intermolecular cyclization between N -arylacrylamides and readily accessible alkyl bromides, which affords diverse range of 3,3-disubstituted oxindoles in moderate to high yields.

Language: Английский

Citations

0
Cu(II)/Photoredox-Catalyzed Aminoacylation of Vinyl Bromides DOI
Guojin Huang, Huanfeng Jiang, Qiang Zeng

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: March 24, 2025

A novel C–C coupling reaction of vinyl bromides with carboxamides has been developed through Cu(OAc)2/photocatalysis. This process features regioselective carboxamido carbon-vinylation under mild conditions. Mechanistic studies suggest that the formation an acyl-Cu(I) intermediate plays a crucial role regard to enabling this transformation.

Language: Английский

Citations

0
Photoinduced pinacol coupling of carbon-carbon bonds via triethoxysilane or Hantzsch Ester DOI
Jianhua Liu,

Gelan Wang,

Chen Chen

et al.

Molecular Catalysis, Journal Year: 2025, Volume and Issue: 579, P. 115088 - 115088

Published: April 5, 2025

Language: Английский

Citations

0
Nickel/Photoredox Dual-Catalyzed, Regioselective 1,2-Carboacylation of Alkenes via Synergistic Alkyl and Benzoyl Radical Coupling DOI

Xian‐Chen He,

Jie Gao, Yang Li

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: May 2, 2025

A regioselective 1,2-carboacylation protocol of alkenes via nickel/photoredox dual catalysis has been successfully developed under mild conditions. wide range alkyl bromides, α-oxocarboxylic acids, and styrenes proved to be compatible the optimized conditions, affording corresponding products in up 91% yields. Mechanistically, key success this approach is temporal orchestration radical generation: nickel-catalyzed halogen atom transfer (XAT) for bromides photoredox-driven decarboxylation acids.

Language: Английский

Citations

0