Research Progress of Sulfoxonium Ylides in the Construction of Five/Six-Membered Nitrogen-Containing Heterocycles DOI
Jiantao Zhang, Cong Zhang,

Zidong Zheng

et al.

Chinese Journal of Organic Chemistry, Journal Year: 2022, Volume and Issue: 42(9), P. 2745 - 2745

Published: Jan. 1, 2022

Language: Английский

Ru(II)-Catalyzed Tunable Cascade Reaction via C–H/C–C Bond Cleavage DOI
Zi Yang, Yue Qi,

Mengqi Yang

et al.

The Journal of Organic Chemistry, Journal Year: 2020, Volume and Issue: 85(20), P. 12960 - 12970

Published: Sept. 17, 2020

A facile synthesis of various 3-(alkoxyalkyl)-1H-indoles from pyrazolidinones, 2-acetylenic ketones, and alkyl alcohols via C–H/C–C bond activation has been developed. The reaction proceeds smoothly under the proper conditions, preliminary mechanistic studies suggest that NaOAc is crucial for C–C activation. advantages present method represent a redox-neutral process exhibit excellent chemo regioselectivity.

Language: Английский

Citations

22
Lithium Bromide-Promoted Formal C(sp3)–H Bond Insertion Reactions of β-Carbonyl Esters with Sulfoxonium Ylides to Synthesize 1,4-Dicarbonyl Compounds DOI

Hailin Guo,

Yuhao Ding,

Jing-Wen Fan

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(10), P. 6974 - 6986

Published: May 4, 2024

A LiBr-promoted formal C(sp3)–H bond insertion reaction between β-carbonyl esters and sulfoxonium ylides is established. This practical has a wide range of substrate scope for both to give variety 1,4-dicarbonyl compounds with 43–94% yields. The features transition-metal-free conditions exclusive C-alkylation chemselectivity. use bench-stable overcomes previous methods that require transition metal as catalysts unstable diazo or toxic haloketones alkylation reagents.

Language: Английский

Citations

2
Quinazolinone-to-Isoquinoline Metamorphosis by Ruthenium-Catalyzed [4+2] Annulation with Sulfoxonium Ylides DOI
Xiaogang Wang, Fei Yuan, Michal Szostak

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(50), P. 10951 - 10957

Published: Dec. 10, 2024

Molecular editing of quinazolinones to isoquinolines by a novel ruthenium-catalyzed [4+2] annulation with sulfoxonium ylides has been developed. The method permits the precise and rapid assembly multisubstituted aminoisoquinolines, class heterocycles that play privileged role in organic synthesis pharmaceutical development. This new catalytic process exhibits programmability, including directed C–H acetylation, nucleophilic cyclization, alcoholysis. Remarkably, various 2-arylquinazolinones could be employed excellent yields broad functional group tolerance. heterocycle-to-heterocycle protocol is compatible green chemistry using an EtOH solvent releasing H2O dimethyl sulfoxide as byproducts.

Language: Английский

Citations

2
Ru(ii)-Catalyzed C–H bond activation/annulation of N-iminopyridinium ylides with sulfoxonium ylides DOI
Xiang Li,

Danlu Li,

Xiaofei Zhang

et al.

Organic & Biomolecular Chemistry, Journal Year: 2022, Volume and Issue: 20(7), P. 1475 - 1479

Published: Jan. 1, 2022

A Ru( ii )-catalyzed C–H bond activation/annulation of N -iminopyridinium ylides with sulfoxonium has been developed, which afforded isocoumarins in moderate to good yields.

Language: Английский

Citations

11
Research Progress of Sulfoxonium Ylides in the Construction of Five/Six-Membered Nitrogen-Containing Heterocycles DOI
Jiantao Zhang, Cong Zhang,

Zidong Zheng

et al.

Chinese Journal of Organic Chemistry, Journal Year: 2022, Volume and Issue: 42(9), P. 2745 - 2745

Published: Jan. 1, 2022

Language: Английский

Citations

11