Review on Microreactors for Photo-Electrocatalysis Artificial Photosynthesis Regeneration of Coenzymes DOI Creative Commons
Haixia Liu, Rui Sun, Yujing Yang

et al.

Micromachines, Journal Year: 2024, Volume and Issue: 15(6), P. 789 - 789

Published: June 15, 2024

In recent years, with the outbreak of global energy crisis, renewable solar has become a focal point research. However, utilization efficiency natural photosynthesis (NPS) is only about 1%. Inspired by NPS, artificial (APS) was developed and utilized in applications such as regeneration coenzymes. APS for coenzyme can overcome problem high consumption comparison to electrocatalytic methods. Microreactors represent promising technology. Compared conventional system, it advantages large specific surface area, fast diffusion small molecules, efficiency. Introducing microreactors lead more efficient, economical, environmentally friendly photosynthesis. This review begins brief introduction microreactors, then summarizes research on traditional regeneration, well photocatalytic photo-electrocatalysis APS, all based compares them corresponding system. Finally, looks forward prospects this

Language: Английский

Organocatalytic Hydrogen Evolution Reaction by Diazaphospholenes DOI

Kaini Xu,

Yushan Zhang, Bing Zhong

et al.

Journal of the American Chemical Society, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 11, 2024

The electrochemical hydrogen evolution reaction (HER) is currently recognized as a prospective way to obtain clean energy. electrocatalysts used are dominantly based on transition metals. In this work, we have demonstrated diazaphospholene (

Language: Английский

Citations

4
Highly Selective Electrocatalytic 1,4‐NADH Regeneration Based on Host–Guest Recognition Mediated by Cucurbit[8]uril on NiO DOI Open Access

Hongxia Ning,

Yizhou Wu, Chang Liu

et al.

Angewandte Chemie International Edition, Journal Year: 2025, Volume and Issue: unknown

Published: March 6, 2025

Abstract Efficient regeneration of nicotinamide adenine dinucleotide (NADH) cofactors, particularly 1,4‐NADH, is crucial for advancing oxidoreductase catalysis. Electrocatalysis provides a promising route 1,4‐NADH regeneration, but an expensive catalyst, typically rhodium organometallic complex, frequently required to guarantee the high selectivity significantly limiting its large‐scale application. Herein, inspired by catalytic pocket and enzyme–substrate interaction in nature, direct electrochemical was designed modification surface nickel oxide (NiO) with cucurbit[8]uril (CB[8]) (denoted as CB[8]–NiO). The host–guest between CB[8] NAD + proved, which similar principle substrate–enzyme‐specific recognition. acted , providing suitable cavity volume accommodate positively charged part . entered approached surface‐adsorbed hydrogen atoms on NiO reaction‐ready configuration achieve regioselective regeneration. Remarkably higher 97.8% CB[8]–NiO obtained at −0.47 V versus reversible electrode (RHE) than that bare (77.4%).

Language: Английский

Citations

0
Highly Selective Electrocatalytic 1,4‐NADH Regeneration Based on Host–Guest Recognition Mediated by Cucurbit[8]uril on NiO DOI Open Access

Hongxia Ning,

Yizhou Wu, Chang Liu

et al.

Angewandte Chemie, Journal Year: 2025, Volume and Issue: unknown

Published: March 6, 2025

Abstract Efficient regeneration of nicotinamide adenine dinucleotide (NADH) cofactors, particularly 1,4‐NADH, is crucial for advancing oxidoreductase catalysis. Electrocatalysis provides a promising route 1,4‐NADH regeneration, but an expensive catalyst, typically rhodium organometallic complex, frequently required to guarantee the high selectivity significantly limiting its large‐scale application. Herein, inspired by catalytic pocket and enzyme–substrate interaction in nature, direct electrochemical was designed modification surface nickel oxide (NiO) with cucurbit[8]uril (CB[8]) (denoted as CB[8]–NiO). The host–guest between CB[8] NAD + proved, which similar principle substrate–enzyme‐specific recognition. acted , providing suitable cavity volume accommodate positively charged part . entered approached surface‐adsorbed hydrogen atoms on NiO reaction‐ready configuration achieve regioselective regeneration. Remarkably higher 97.8% CB[8]–NiO obtained at −0.47 V versus reversible electrode (RHE) than that bare (77.4%).

Language: Английский

Citations

0
In situ NADH regeneration coupled to enzymatic CO2 reduction: from fundamental concepts to recent advances DOI
Neha Gupta, Arpita Sarkar, Soumya Kanti Biswas

et al.

Journal of environmental chemical engineering, Journal Year: 2025, Volume and Issue: unknown, P. 116657 - 116657

Published: April 1, 2025

Language: Английский

Citations

0
Facet-Engineered Copper Electrocatalysts Enable Sustainable NADH Regeneration with High Efficiency DOI
Shuo Sun, Yizhou Wu,

Yunxuan Ding

et al.

Journal of the American Chemical Society, Journal Year: 2025, Volume and Issue: unknown

Published: April 30, 2025

Electrochemical regeneration of the nicotinamide cofactor (NADH) provides a sustainable approach to enzymatic reactions. However, low productivity and selectivity bioactive 1,4-NADH limit its broad applications. The hydrogenation NAD+ at electrode surface is strongly coupled conformation adsorbed NAD*, formation hydrogen (Had), Had transfer NAD*. Therefore, searching for materials with suitable NAD* conformation, energy, rapid becomes key task research. In this study, (111) facet Cu was found exhibit higher 86.4%, compared 50.4% 57.4% (100) (110) facets, respectively. Density functional theory (DFT) calculations revealed that high Cu(111) stemmed from favorable reduced barrier. Subsequently, nanowire (111)-dominant abundant grain boundaries, Cugb(111), constructed. kinetic analysis DFT demonstrated boundaries reduce reaction barrier formation. A record-high 73.5 μmol h-1 cm-2 achieved by while well-maintained 84.7%. This study elucidates effects crystal facets on regulating 1,4-NADH, providing pathway renewable energy-powered, high-efficiency green biomanufacturing.

Language: Английский

Citations

0
Establishing the Thermodynamic Cards of Dipine Models’ Oxidative Metabolism on 21 Potential Elementary Steps DOI Creative Commons
Guang‐Bin Shen,

Shun-Hang Gao,

Yanwei Jia

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(15), P. 3706 - 3706

Published: Aug. 5, 2024

Dipines are a type of important antihypertensive drug as L-calcium channel blockers, whose core skeleton is the 1,4-dihydropyridine structure. Since dihydropyridine ring key structural factor for biological activity, thermodynamics aromatization significant feature parameter understanding mechanism and pathways dipine metabolism in vivo. Herein, 4-substituted-phenyl-2,6-dimethyl-3,5-diethyl-formate-1,4-dihydropyridines refined structurally closest models to investigate thermodynamic potential oxidative metabolism. In this work, cards models' on 21 elementary steps acetonitrile have been established. Based cards, properties related intermediates acting electrons, hydrides, hydrogen atoms, protons, two ions (atoms) donors discussed. Moreover, applied evaluate redox properties, judge or reveal possible models.

Language: Английский

Citations

1
Review on Microreactors for Photo-Electrocatalysis Artificial Photosynthesis Regeneration of Coenzymes DOI Creative Commons
Haixia Liu, Rui Sun, Yujing Yang

et al.

Micromachines, Journal Year: 2024, Volume and Issue: 15(6), P. 789 - 789

Published: June 15, 2024

In recent years, with the outbreak of global energy crisis, renewable solar has become a focal point research. However, utilization efficiency natural photosynthesis (NPS) is only about 1%. Inspired by NPS, artificial (APS) was developed and utilized in applications such as regeneration coenzymes. APS for coenzyme can overcome problem high consumption comparison to electrocatalytic methods. Microreactors represent promising technology. Compared conventional system, it advantages large specific surface area, fast diffusion small molecules, efficiency. Introducing microreactors lead more efficient, economical, environmentally friendly photosynthesis. This review begins brief introduction microreactors, then summarizes research on traditional regeneration, well photocatalytic photo-electrocatalysis APS, all based compares them corresponding system. Finally, looks forward prospects this

Language: Английский

Citations

0