Journal of Separation Science,
Journal Year:
2024,
Volume and Issue:
47(16)
Published: Aug. 1, 2024
Molecularly
imprinted
polymers,
a
type
of
special
polymer
materials,
are
widely
used
in
biosensing
and
other
fields
due
to
their
ability
specifically
recognize
target
molecules,
often
called
"artificial
receptors.".
Nowadays,
researchers
constantly
exploring
new
design
synthesis
methods
for
molecularly
materials
improve
the
selectivity
sensitivity
materials.
Among
them,
selection
functional
monomers
has
attracted
great
attention.
This
review
comprehensively
analyzes
discusses
monomers.
The
most
commonly
among
different
types
templates
screened
based
on
structural
properties
template
including
ion-imprinted
protein-imprinted
bacterial
polymers.
rich
binding
sites
group
multifunctional
also
highlighted
advance
development
molecular
imprinting
technology.
article
further
explores
current
challenges
prospects
emphasizes
multiplex
experiments
computer
simulations
as
important
directions
future
research.
provides
comprehensive
information
constructive
guidelines
selecting
areas
such
analytical
chemistry
biosensors.
Advanced Materials,
Journal Year:
2022,
Volume and Issue:
34(42)
Published: June 23, 2022
Abstract
Molecular
imprinting
technology
(MIT)
produces
artificial
binding
sites
with
precise
complementarity
to
substrates
and
thereby
is
capable
of
exquisite
molecular
recognition.
Over
five
decades
evolution,
it
predicted
that
the
resulting
host
imprinted
materials
will
overtake
natural
receptors
for
research
application
purposes,
but
in
practice,
this
has
not
yet
been
realized
due
unsustainability
their
life
cycles
(i.e.,
precursors,
creation,
use,
recycling,
end‐of‐life).
To
address
issue,
greenificated
molecularly
polymers
(GMIPs)
are
a
new
class
plastic
antibodies
have
approached
sustainability
by
following
one
or
more
greenification
principles,
while
also
demonstrating
far‐reaching
applications
compared
counterparts.
In
review,
most
recent
developments
delicate
design
advanced
GMIPs
six
fast‐growing
emerging
fields
surveyed,
namely
biomedicine/therapy,
catalysis,
energy
harvesting/storage,
nanoparticle
detection,
gas
sensing/adsorption,
environmental
remediation.
addition,
distinct
features
highlighted,
optimal
means
utilize
these
attaining
incredibly
discussed.
Importantly,
obscure
technical
challenges
MIT
revealed,
conceivable
solutions
offered.
Lastly,
several
perspectives
on
future
directions
proposed.
Talanta Open,
Journal Year:
2023,
Volume and Issue:
8, P. 100243 - 100243
Published: July 8, 2023
Hydrogels
have
a
significant
impact
on
the
fields
of
biological
study
and
medical
diagnosis.
They
are
becoming
more
useful
in
bioanalytical
biosensing
applications.
The
intriguing
new
nanomaterials
quantum
dots-hydrogel
composites
gained
lot
interest
because
their
unmatched
biocompatibility
tolerable
biodegradability,
which
opens
up
wide
range
possible
Focusing
synthesis
techniques,
this
review
describes
current
developments
composites,
such
as
hydrogel
gelation
dots
(QDs)
solution,
inserting
prepared
QDs
into
hydrogels
after
gelation,
generating
situ
inside
preformed
gel,
cross-linking
through
QDs.
Biomedical
applications
bioimaging
specifically
examined,
then
inherent
problems
design
optimisation,
biocompatibility,
bimodal
applications,
well
potential
future
development,
discussed.
Molecules,
Journal Year:
2023,
Volume and Issue:
28(1), P. 335 - 335
Published: Jan. 1, 2023
The
abuse
and
residues
of
antibiotics
have
a
great
impact
on
the
environment
organisms,
their
determination
has
become
very
important.
Due
to
low
contents,
varieties
complex
matrices,
effective
recognition,
separation
enrichment
are
usually
required
prior
determination.
Molecularly
imprinted
polymers
(MIPs),
kind
highly
selective
polymer
prepared
via
molecular
imprinting
technology
(MIT),
used
widely
in
analytical
detection
antibiotics,
as
adsorbents
solid-phase
extraction
(SPE)
recognition
elements
sensors.
Herein,
recent
advances
MIPs
for
antibiotic
residue
analysis
reviewed.
Firstly,
several
new
preparation
techniques
detecting
briefly
introduced,
including
surface
imprinting,
nanoimprinting,
living/controlled
radical
polymerization,
multi-template
multi-functional
monomer
dummy
template
imprinting.
Secondly,
SPE
modes
based
summarized,
namely
packed
SPE,
magnetic
dispersive
matrix
extraction,
microextraction,
stir-bar
sorptive
pipette-tip
SPE.
Thirdly,
basic
principles
MIP-based
sensors
three
sensing
modes,
electrochemical
sensing,
optical
mass
also
outlined.
Fourthly,
research
progress
molecularly
SPEs
(MISPEs)
electrochemical/optical/mass
various
environmental
food
samples
since
2018
comprehensively
reviewed,
sulfonamides,
quinolones,
β-lactams
so
on.
Finally,
application
prospects
Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
96(16), P. 6417 - 6425
Published: April 12, 2024
Molecular
imprinting-based
surface-enhanced
Raman
scattering
(MI-SERS)
sensors
have
shown
remarkable
potential
from
an
academic
standpoint.
However,
their
practical
applications,
especially
in
the
detection
of
large-size
protein
(≥10
nm),
face
challenges
due
to
lack
versatile
sensing
strategies
and
nonspecific
fouling
matrix
species.
Herein,
we
propose
a
reporter
inspector
mechanism
(RRIM)
implemented
on
protein-imprinted
polydopamine
(PDA)
layer
coated
SERS
active
substrate.
In
RRIM,
after
recognition,
permeability
PDA
imprinted
cavities
undergoes
changes
that
are
scrutinized
by
molecules.
Target
proteins
can
specifically
bind
fully
occupy
cavities,
whereas
species
cannot.
Then,
molecules
with
suitable
size
introduced
serve
as
both
inspectors
recognition
status
inducers
signal,
which
only
penetrate
through
vacant
nonspecifically
filled
cavities.
Consequently,
signal
exclusively
originate
specific
binding
target
proteins,
while
is
curbed.
The
RRIM
enables
reproducible
quantitation
cyanobacteria-specific
model
phycocyanin,
at
level
down
2.6
×
10
