From Fundamental Amyloid Protein Self-Assembly to Development of Bioplastics

Biomacromolecules, Journal Year: 2023, Volume and Issue: 25(1), P. 5 - 23

Published: Dec. 26, 2023

Proteins can self-assemble into a range of nanostructures as result molecular interactions. Amyloid nanofibrils, one them, were first discovered with regard to the relevance neurodegenerative diseases but now have been exploited building blocks generate multiscale materials designed functions for versatile applications. This review interconnects mechanism amyloid fibrillation, current approaches synthesizing protein-based materials, and application in bioplastic development. We focus on fundamental structures self-assembled fibrils how external factors affect protein aggregation optimize process. Protein self-assembly is essentially autonomous congregation smaller units larger, organized structures. Since properties be manipulated by changing intrinsic conditions, serves an excellent block Building these principles, general processing methods pathways from raw sources mature state are proposed, providing guide development large-scale production. Additionally, this discusses diverse nanofibrils they utilized bioplastics. The economic feasibility bioplastics also compared conventional plastics production scenarios, supporting their potential sustainable future

Language: Английский

Dynamic Properties of β-Casein Fibril Adsorption Layers at the Air–Water Interface

Polymers, Journal Year: 2025, Volume and Issue: 17(8), P. 1075 - 1075

Published: April 16, 2025

Although the formation of layers fibrillar aggregates at liquid–liquid and liquid–gas interfaces can significantly increase stability disperse systems, like foams emulsions, any information on their structure properties is rather limited. In present work, surface adsorption fibrils intrinsically disordered β-casein are investigated. For unpurified dispersions this protein, dynamic elasticity proved to be close values for native protein solutions. This behavior typical globular proteins. However, previously studied another κ-casein, do not demonstrate similarity. The contribution becomes noticeable only after purification from impurities high activity. increases up 48 mN/m two cycles, i.e., 4 times higher than steady-state same bulk concentrations.

Language: Английский

Mixed Adsorption Mono- and Multilayers of ß-Lactoglobulin Fibrils and Sodium Polystyrene Sulfonate

Colloids and Interfaces, Journal Year: 2024, Volume and Issue: 8(6), P. 61 - 61

Published: Nov. 11, 2024

The formation of beta-lactoglobulin (BLG)/sodium polystyrene sulfonate (PSS) complexes decelerates the change in surface properties mixed solutions with age and increases steady-state dilational elasticity a narrow PSS concentration range. At same time, changes are accelerated dispersions BLG fibrils without due to influence small peptides coexisting fibrils. A decrease peptide as result dispersion purification leads slower at low concentrations. increase polyelectrolyte results an fibril/PSS complex very slow if exceeds certain critical value. latter effect is consequence large aggregates electrostatic adsorption barrier. consecutive regular multilayers liquid–gas interface. multilayer noticeably number layers from four six agreement previous on oppositely charged synthetic polyelectrolyte, presumably heterogeneity first layer. dynamic approaches 250 mN/m, indicating that they can effectively stabilize foams emulsions.

Language: Английский