Engineered nanoparticles for imaging and targeted drug delivery in hepatocellular carcinoma

Experimental Hematology and Oncology, Journal Year: 2025, Volume and Issue: 14(1)

Published: April 30, 2025

Liver cancer, notably hepatocellular carcinoma (HCC), poses a significant global health burden due to its high fatality rates. Conventional antitumor medications face challenges, including poor targeting, toxicity, and drug resistance, leading suboptimal clinical outcomes. This review focused on nanoparticle use in diagnosing delivering medication for HCC, aiming advance the development of nanomedicines improved treatment As an emerging frontier science technology, nanotechnology has shown great potential, especially precision medicine personalized treatment. The success nanosystems is attributable their smaller size, biocompatibility, selective tumor accumulation, lower toxicity. Nanoparticles, as central part innovation, have emerged field medical diagnostics therapeutics overcome various limitations conventional chemotherapy, thus offering promising applications selectivity, earlier more precise diagnosis cancers, treatment, overcoming resistance. Nanoparticles play crucial role delivery imaging with body acting system target deliver drugs or diagnostic reagents specific organs tissues, helping accurately diagnose therapies while minimizing damage healthy tissues. They protect from early degradation increase biological half-life.

Language: Английский

Hydrolytic degradation of nerve agent simulants accelerated by Host-Guest gold nanozymes

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 163290 - 163290

Published: May 1, 2025

Language: Английский