Expert Opinion on Drug Delivery,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 29, 2025
Drug
administration
is
ubiquitous
in
the
healthcare
field,
and
it
crucial
to
optimize
drug
delivery
methods
improve
efficacy,
reduce
systemic
toxicity,
enhance
patient
compliance
Thermogels
have
shown
immense
potential
due
their
injectability,
biocompatibility,
ability
provide
localized
sustained
release.
This
paper
discusses
unique
properties
of
thermogel
relation
kinetics
suitability
as
a
carrier.
Different
considerations
applications
systems
(DDS)
were
highlighted
challenges
enter
market
discussed.
A
comprehensive
literature
search
was
conducted
using
major
databases
such
PubMed,
Scopus,
Web
Science.
The
employed
relevant
keywords
identify
studies
on
DDS.
Clinicaltrials.gov
also
utilized
determine
current
state
clinical
studies.
Nonetheless,
holds
great
promise
for
future
DDS
with
research
achieving
greater
heights
terms
complexity
pursuits.
Their
flexibility
fabrication
modularity
manner
makes
material
tailor
different
be
integrated
into
various
biomedical
disciplinaries.
The FASEB Journal,
Journal Year:
2025,
Volume and Issue:
39(5)
Published: March 6, 2025
Botanical
drugs
and
probiotic
supplements
present
safer
alternative
options
for
the
prevention
treatment
of
osteoporosis
(OP).
However,
pathological
disorders
gut
microbiota
specific
properties
probiotics
traditional
Chinese
medicine
(TCM)
significantly
limit
their
therapeutic
efficacy.
Given
favorable
synergistic
complementary
effects
between
herbal
medicines,
a
creative
combination
these
approaches
may
address
issue
current
limited
A
comprehensive
analysis
is
necessary
to
provide
detailed
review
potential
combination,
mechanisms
behind
synergy,
scientific
applications,
future
developments.
There
exists
complex
relationship
OP,
underlying
regulatory
are
multidimensional,
involving
production
pro-inflammatory
metabolites,
immune
system
disruption,
impairment
intestinal
mucosal
barrier.
Furthermore,
we
analyzed
connections
probiotics,
TCM,
combined
applications.
We
highlighted
principle
gain
substantial
organic
which
facilitates
release
active
substances
in
increases
bioavailability
enhances
delivery
efficiency,
exerts
effects.
The
use
TCM
offers
safe
effective
strategy
managing
OP
presents
an
innovative
promising
direction
development
modern
phytomedicine.
Expert Opinion on Drug Delivery,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 29, 2025
Drug
administration
is
ubiquitous
in
the
healthcare
field,
and
it
crucial
to
optimize
drug
delivery
methods
improve
efficacy,
reduce
systemic
toxicity,
enhance
patient
compliance
Thermogels
have
shown
immense
potential
due
their
injectability,
biocompatibility,
ability
provide
localized
sustained
release.
This
paper
discusses
unique
properties
of
thermogel
relation
kinetics
suitability
as
a
carrier.
Different
considerations
applications
systems
(DDS)
were
highlighted
challenges
enter
market
discussed.
A
comprehensive
literature
search
was
conducted
using
major
databases
such
PubMed,
Scopus,
Web
Science.
The
employed
relevant
keywords
identify
studies
on
DDS.
Clinicaltrials.gov
also
utilized
determine
current
state
clinical
studies.
Nonetheless,
holds
great
promise
for
future
DDS
with
research
achieving
greater
heights
terms
complexity
pursuits.
Their
flexibility
fabrication
modularity
manner
makes
material
tailor
different
be
integrated
into
various
biomedical
disciplinaries.
