Polydiacetylene (PDA) Embedded Polymer-Based Network Structure for Biosensor Applications

Gels, Journal Year: 2025, Volume and Issue: 11(1), P. 66 - 66

Published: Jan. 15, 2025

Biosensors, which combine physical transducers with biorecognition elements, have seen significant advancement due to the heightened interest in rapid diagnostic technologies across a number of fields, including medical diagnostics, environmental monitoring, and food safety. In particular, polydiacetylene (PDA) is gaining attention as an ideal material for label-free colorimetric biosensor development its unique color-changing properties response external stimuli. PDA forms through self-assembly diacetylene monomers, color change occurring conjugated backbone twists stimuli such temperature, pH, chemical interactions. This enables detection biomarkers, metal ions, toxic compounds. Moreover, combination polymeric structures hydrogels further enhances sensitivity structural stability PDA-based biosensors, making them reliable effective complex biological conditions. review comprehensively examines recent research trends applications PDA–polymeric structure hybrid while discussing future directions potential advancements this field.

Language: Английский

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Thermo-sensitive polycaprolactone coacervates for preventing protein aggregation under thermal stress

Journal of Materials Chemistry B, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Inspired from heat shock proteins (HSPs), a thermo-sensitive coacervate-forming polycaprolactone (CPCL) was designed as natural chaperone mimic to protect thermal stress. Unlike the coil-globule polymers of poly(N-isopropyl acrylamide) (PNIPAM), as-designed CPCL underwent partial dehydration during heating, characterizing it polymer. With its ability transform between coil and coacervate states in response temperature, theCPCL spontaneously captured released targeted proteins, thereby behaving like HSPs. Remarkably, compared with PNIPAM homopolymer, provided more efficient protection for by inhibiting heat-induced aggregation above melting temperature (Tm). Taken together, we envision that excellent biodegradability biocompatibility could be safe excipient protein against damage without separation.

Language: Английский

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Mechanical reinforcement and confinement in elastomeric corn starch/bentonite nanocomposites

Polymer, Journal Year: 2024, Volume and Issue: 312, P. 127625 - 127625

Published: Sept. 14, 2024

Language: Английский

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Dynamics and viscoelasticity of potato and corn starch bio-polymers reinforced with bentonite nanoclay

European Polymer Journal, Journal Year: 2024, Volume and Issue: 220, P. 113425 - 113425

Published: Sept. 3, 2024

Language: Английский

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