Nanomedicine and clinical diagnostics part I: applications in conventional imaging (MRI, X-ray/CT, and ultrasound)

Nanomedicine, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 16

Published: Dec. 11, 2024

Integrating nanotechnologies in diagnostic imaging presents a promising step forward compared to traditional methods, which carry certain limitations. Conventional routes, such as X-ray/computed tomography and magnetic resonance imaging, derive significant advantages from nanoparticles (NPs), allow researchers clinicians overcome some of the limitations agents. In this literature review, we explore recent advancements nanomaterials being applied conventional techniques by exploring relevant reviews original research papers (e.g. experimental models theoretical model studies) literature. Collectively, there are numerous currently examined for use modalities, each technique has unique NPs with properties that can be manipulated answer an array clinical questions specific modality. There still challenges consider, including getting regulatory approval routine about long-term biocompatibility, collectively emphasize need continued facilitate integration nanotechnology into practice. Most importantly, is strong, collaborative efforts between researchers, biomedical engineers, clinicians, industry stakeholders, necessary bridge persistent gap translational ideas implementation settings.

Language: Английский

Targeted Molecular Imaging and Therapy Based on Nuclear and Optical Technologies

Biological and Pharmaceutical Bulletin, Journal Year: 2024, Volume and Issue: 47(6), P. 1066 - 1071

Published: May 31, 2024

Both nuclear and optical imaging are used for in vivo molecular imaging. Nuclear displays superior quantitativity, it permits deep tissues. Thus, this method is widely clinically. Conversely, because of the low permeability visible to near-IR light living animals, difficult visualize tissues via However, at these wavelengths has no ionizing effect, can be without any restrictions terms location. Furthermore, signals controlled accomplish target-specific medicine phototherapy have also evolved permit targeted-specific In targeted therapy, beta emitters conventionally used, but alpha received significant attention recently. Concerning phototherapy, photoimmunotherapy with was approved Japan 2020. article, therapy utilizing technologies discussed.

Language: Английский