ACS Applied Materials & Interfaces,
Journal Year:
2023,
Volume and Issue:
15(36), P. 42404 - 42412
Published: Aug. 29, 2023
Metal-organic
frameworks
(MOF)
are
promising
candidates
for
the
construction
of
artificial
nanozymes
and
have
found
applications
in
many
fields.
However,
preparation
nanosized
MOF
materials
with
high
performance
good
dispersibility
is
still
a
big
challenge
great
demand
as
signal
labels
immunoassays.
In
this
work,
hierarchically
structured
highly
dispersible
nanoparticles
were
facilely
prepared
one-pot
method.
Self-assembled
micelles
from
PEGylated
hematin
used
templates
to
mediate
formation
zeolitic
imidazole
framework-8
(ZIF-8)
aqueous
solution.
The
encapsulation
ZIF-8
produces
well-dispersed
generates
dual-confinement
effects
catalytic
hematin.
Owing
hierarchical
structures,
formed
show
enhanced
peroxidase-like
activity
enable
persistent
chemiluminescence
behaviors
luminol
system.
Sandwich-type
immunoassays
carcinoembryonic
antigen
(CEA)
proposed
using
labels,
analytical
performances
achieved.
combination
self-assembly
biomineralization
may
open
new
avenues
development
nanomaterials.
Case Studies in Chemical and Environmental Engineering,
Journal Year:
2024,
Volume and Issue:
9, P. 100753 - 100753
Published: May 16, 2024
The
chemical
compound
nicotine,
specifically
3-(1-methyl-2-pyrrolidinyl)
pyridine,
is
a
notable
xenobiotic
under
investigation
in
the
realm
of
electrochemical
biosensors.
This
article
emphasizes
nature
this
substance
and
its
impact
on
human
body.
Different
species
with
pharmacological,
therapeutic,
industrial,
food-related,
environmental
origins
can
now
be
detected
using
sensors.
Nicotine,
an
addictive
tobacco
products
electronic
cigarettes
(e-cigs),
recognized
for
increasing
risk
cardiovascular
respiratory
disorders.
Careful
real-time
monitoring
nicotine
exposure
critical
alleviating
potential
health
impacts
not
just
smokers
but
also
those
exposed
to
second-hand
third-hand
smoke.
Monitoring
requires
suitable
sensing
material
detect
selectively
testing
free-living
conditions
standard
environment.
A
biosensor
consists
sensitive
biological
system
detector
appropriate
transducers
obtaining
output
signals.
applications
these
devices
include
screening,
detection
contaminants,
farming,
routine
medical
examinations.
Critical
factors
widespread
commercialization
will
product's
selectivity,
sensitivity,
stability,
lower
production
costs.
Scientists
have
been
working
developing
nano
high
degree
sensitivity
selectivity
recognition
biomarkers
immune
responses
cancer.
An
analysis
various
parameters,
including
Limit
Detection
(LOD)
concentration
within
pH
range
(7-7.4),
has
conducted.
objective
enhance
expand
linear
range,
optimize
optical
electrical
properties.
delves
into
optimization
sensors
biosensors
from
perspective,
highlighting
positive
negative
effects
as
well
metabolic
pathways
study
categorizes
evaluates
latest
based
their
generation
(electron
transfer
between
multilayers)
methods
(modification
types
or
direct
electrodes).
strengths
weaknesses
each
are
scrutinized
over
past
15
years,
focus
solely
Angewandte Chemie International Edition,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 12, 2025
Abstract
Nanozymes
with
atomically
dispersed
metal
sites
(ADzymes),
especially
single‐atom
nanozymes,
have
attracted
widespread
attention
in
recent
years
due
to
their
unique
advantages
mimicking
the
active
of
natural
enzymes.
These
nanozymes
not
only
maximize
exposure
catalytic
but
also
possess
superior
activity
performance,
achieving
challenging
reactions.
position
ADzymes
as
highly
promising
candidates
field
sensing
and
biosensing.
This
review
summarizes
classification
properties
ADzymes,
systematically
highlighting
some
typical
regulation
strategies
involving
central
metal,
coordination
environment,
etc.,
achieve
catalytical
activity,
specificity,
multifunctionality.
Then,
we
present
advances
different
fields,
including
colorimetry,
fluorescence,
electrochemistry,
chemiluminescence,
photoelectrochemistry,
electrochemiluminescence.
Taking
advantage
resultant
show
great
potential
goal
sensitivity,
selectivity
accuracy
for
detection
various
targets.
Specifically,
underlying
mechanisms
terms
signal
amplification
were
discussed
detail.
Finally,
current
challenges
perspectives
on
development
advanced
are
discussed.
ACS Applied Materials & Interfaces,
Journal Year:
2023,
Volume and Issue:
15(36), P. 42404 - 42412
Published: Aug. 29, 2023
Metal-organic
frameworks
(MOF)
are
promising
candidates
for
the
construction
of
artificial
nanozymes
and
have
found
applications
in
many
fields.
However,
preparation
nanosized
MOF
materials
with
high
performance
good
dispersibility
is
still
a
big
challenge
great
demand
as
signal
labels
immunoassays.
In
this
work,
hierarchically
structured
highly
dispersible
nanoparticles
were
facilely
prepared
one-pot
method.
Self-assembled
micelles
from
PEGylated
hematin
used
templates
to
mediate
formation
zeolitic
imidazole
framework-8
(ZIF-8)
aqueous
solution.
The
encapsulation
ZIF-8
produces
well-dispersed
generates
dual-confinement
effects
catalytic
hematin.
Owing
hierarchical
structures,
formed
show
enhanced
peroxidase-like
activity
enable
persistent
chemiluminescence
behaviors
luminol
system.
Sandwich-type
immunoassays
carcinoembryonic
antigen
(CEA)
proposed
using
labels,
analytical
performances
achieved.
combination
self-assembly
biomineralization
may
open
new
avenues
development
nanomaterials.
