Multiplex Detection of Biomarkers Empowered by Nanomaterials DOI Creative Commons
Zongbo Li, Mingquan Guo, Wenwan Zhong

et al.

Precision Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 21, 2025

Language: Английский

Bidirectionally Favorable Platform: A Dual-Targeting Probe-Encoded Maple Leaf-Type Fluorescent Lateral Flow Immunoassay for Multiple Biomarker Detection DOI
Shen Zeng,

Wanchao Zuo,

Huilin Zhang

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 17, 2025

In the traditional multiplexed lateral flow immunoassay (LFIA), different detection probes against targets are necessary. However, relative complexity and high cost of probe preparation, as well insufficient user-friendliness, limit application LFIA in disease diagnosis. Here, we reported a bidirectionally favorable (BDF-LFIA) platform to maximize convenience for both manufacturers users. Red-emitting time-resolved fluorescent nanoparticles were coated with antibodies recognize multiple simultaneously, which greatly simplified preparation by manufacturers. Ultrabright green-emitting gold nanoclusters pre-embedded on test line reference signal achieve target concentration-dependent maple leaf-type hue readout from green yellow red, was quite user-friendly. Taking cancer biomarkers alpha-fetoprotein carcinoembryonic antigen examples, this assay achieved visual 2 ng/mL. Compared conventional LFIA, BDF-LFIA could generate more discernible around threshold concentration targets. Moreover, successfully diagnosed 54 clinical samples. Overall, showed bidirectional benefits users provided new concept detection.

Language: Английский

Citations

0
Nose-to-brain delivery of gold nanozyme with cascade effect for bacterial meningitis therapy DOI
Shujie Deng, Xinyu Zhou,

Xiaopeng Zou

et al.

Rare Metals, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 25, 2025

Language: Английский

Citations

0
Catalytic activity nanozymes for microbial detection DOI
Zhengyu Jin, Guodong Huang, Yang Song

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 534, P. 216578 - 216578

Published: March 4, 2025

Language: Английский

Citations

0
Bimetallic organic framework nanozyme-driven aptasensor for colorimetric and photothermal dual-modal detection of kanamycin DOI
Gengli Huang, Shuo Qi, Xiaodong Lü

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106331 - 106331

Published: March 1, 2025

Language: Английский

Citations

0
Multiplex Detection of Biomarkers Empowered by Nanomaterials DOI Creative Commons
Zongbo Li, Mingquan Guo, Wenwan Zhong

et al.

Precision Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 21, 2025

Language: Английский

Citations

0