Turn-On NIR-II Polymer Dots with Large Stokes Shift for In Vivo Visualizing Dynamical Brain Zinc in Alzheimer’s Disease Mouse DOI

Zhen Shi,

Junyong Sun, Xiaomei Dai

et al.

The Journal of Physical Chemistry Letters, Journal Year: 2024, Volume and Issue: unknown, P. 12129 - 12137

Published: Nov. 27, 2024

It is a critical and broad prospect to evaluate ion levels monitor their dynamic changes in the brain for early diagnosis, in-depth mechanism investigation, accurate staging of neurodegenerative diseases including Alzheimer's disease (AD). still great challenge vivo track Zn

Language: Английский

Polyfunctional Arylamine Based Nanofiltration Membranes with Enhanced Aggressive Organic Solvents Resistance DOI
Yun Shen, Yiming Li,

Shideng Yuan

et al.

Nano Letters, Journal Year: 2024, Volume and Issue: 24(33), P. 10169 - 10176

Published: Aug. 7, 2024

Organic solvent nanofiltration (OSN) membranes with high separation performance and excellent stability in aggressive organic solvents are urgently desired for chemical separation. Herein, we utilized a polyfunctional arylamine tetra-(4-aminophenyl) ethylene (TAPE) to prepare highly cross-linked polyamide membrane low molecular weight cut-off (MWCO) of 312 Da. Owing its propeller-like conformation, TAPE formed micropores within the provided fast transport channels. Importantly, rigid conjugated skeleton connectivity between effectively prevented expansion matrix solvents. The maintained even immersed

Language: Английский

Citations

2
Optical Transparency Windows in Near‐Infrared and Short‐Wave Infrared for the Skin, Skull, and Brain: Fluorescence Bioimaging Using PbS Quantum Dots DOI

Jinghan Qu,

Iuliia Golovynska, Jiantao Liu

et al.

Journal of Biophotonics, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 24, 2024

ABSTRACT Fluorescence imaging (FI) employing near‐infrared (NIR) light within the range of ~750–1350 nm enables biomedical several millimeters beneath tissue surface. More recent investigations into short‐wave IR (SWIR) transparency windows between ~1550–1870 and 2100–2300 highlight their superior capabilities. This research presents a comparison IR‐FI PbS quantum dots, emitting at 990, 1310, 1580 nm, through mouse scalp skin, skull, brain. The SWIR fluorescence is most effectively transmitted signal, showing particularly significant enhancement when passing which causes high scattering. For analysis results propagation organs, spectra attenuation, absorption, scattering coefficients are measured. In view imaging, attenuation due to more destructive factor. Hence, spatial resolution contrast can be improved by operating in decreased

Language: Английский

Citations

1
A NIR-II Fluorescence Probe for Tracking Oxidative Stress in Plants Induced by Metal Contaminants DOI

Gaowei Deng,

Lihe Sun, Fang Zeng

et al.

Analytical Methods, Journal Year: 2024, Volume and Issue: 16(48), P. 8316 - 8323

Published: Jan. 1, 2024

An activatable NIR-II probe has been developed for tracking metal ion-induced oxidative stress in plants, which generates fluorescence signals response to NO and is good advancing plant health assessment environmental monitoring.

Language: Английский

Citations

1
The Second Near-Infrared (NIR-II) Window Excitable/Emissive Organic/Polymeric Fluorescent Molecules for Bioimaging Application DOI Creative Commons
Guannan Liu, Chenguang Wang, Geyu Lu

et al.

Journal of Innovative Optical Health Sciences, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 15, 2024

The fluorescence imaging (FLI) in the second near-infrared window (NIR-II, 1000–1700[Formula: see text]nm) has attracted considerable attention past decade. In contrast to conventional NIR-I excitation (808[Formula: text]nm/980[Formula: text]nm), FLI with NIR-II (1064[Formula: text]nm/other wavelength beyond 1000[Formula: can afford deeper tissue penetration depth high clarity due merits of suppressed photon scattering and diminished autofluorescence. this review, we have summarized excitable/emissive organic/polymeric fluorophores recently developed. characteristics these such as chemical structures photophysical properties also been critically discussed. Furthermore, latest development noninvasive vivo was highlighted. ideal results emphasized importance enabling deep high-resolution imaging. Finally, a perspective on challenges prospects We expected review will be served source inspiration for researchers, stimulating creation novel excitable fostering bioimaging applications.

Language: Английский

Citations

0
Molecular Design of Nir-Ii Organic Fluorescent Probe Based on Adjusting the Shielding Unit DOI

Hua-chao Tian,

Minxia Liu,

Zi-long Cao

et al.

Published: Jan. 1, 2024

Organic fluorophores are extensively utilized in the second near-infrared window (NIR-II) for bioimaging applications, owing to their superior biocompatibility and favorable metabolic properties. This study focused on shielding unit-donor-acceptor-donor-shielding unit (S-D-A-D-S) architecture of organic π-conjugated molecules, which mitigates aggregation-induced quenching by modification terminal units. The introduction thiophene groups as donor units serves augment conjugation length, thereby inducing a redshift fluorescence wavelength with an increasing number Density functional theory (DFT) time-dependent DFT (TD-DFT) methods were employed investigate frontier molecular orbitals, electronic absorption, spectra designed compounds. An in-depth analysis elucidates mechanisms impact properties results indicate that phenoxazine group (POZ) linked at position 'a' provides most pronounced effect. Extending POZ-a compound extend within NIR-II spectrum, POZ-5 achieving up 1308 nm aqueous environment. Furthermore, modulating bridge's length enables precise control over compound's wavelength, luminescence intensity color purity, negligible from performance.

Language: Английский

Citations

0
Molecular Design of Nir-Ii Organic Fluorescent Probe Based on Adjusting the Shielding Unit DOI

Hua-chao Tian,

Minxia Liu,

Zi-long Cao

et al.

Published: Jan. 1, 2024

Organic fluorophores are extensively utilized in the second near-infrared window (NIR-II) for bioimaging applications, owing to their superior biocompatibility and favorable metabolic properties. This study focused on shielding unit-donor-acceptor-donor-shielding unit (S-D-A-D-S) architecture of organic π-conjugated molecules, which mitigates aggregation-induced quenching by modification terminal units. The introduction thiophene groups as donor units serves augment conjugation length, thereby inducing a redshift fluorescence wavelength with an increasing number Density functional theory (DFT) time-dependent DFT (TD-DFT) methods were employed investigate frontier molecular orbitals, electronic absorption, spectra designed compounds. An in-depth analysis elucidates mechanisms impact properties results indicate that phenoxazine group (POZ) linked at position 'a' provides most pronounced effect. Extending POZ-a compound extend within NIR-II spectrum, POZ-5 achieving up 1308 nm aqueous environment. Furthermore, modulating bridge's length enables precise control over compound's wavelength, luminescence intensity color purity, negligible from performance.

Language: Английский

Citations

0
[ DOI

Xiaoqi Li,

Xiao Sun,

Hua Lin

et al.

PubMed, Journal Year: 2024, Volume and Issue: 41(3), P. 620 - 626

Published: June 25, 2024

Near-infrared fluorescence imaging technology, which possesses superior advantages including real-time and fast imaging, high spatial temporal resolution, deep tissue penetration, shows great potential for tumor

Language: Английский

Citations

0
Molecular design of NIR-II organic fluorescent probe based on adjusting the shielding unit DOI

Hua-chao Tian,

M.H. Liu,

Zi-long Cao

et al.

Journal of Luminescence, Journal Year: 2024, Volume and Issue: 275, P. 120827 - 120827

Published: Aug. 6, 2024

Language: Английский

Citations

0
Turn-On NIR-II Polymer Dots with Large Stokes Shift for In Vivo Visualizing Dynamical Brain Zinc in Alzheimer’s Disease Mouse DOI

Zhen Shi,

Junyong Sun, Xiaomei Dai

et al.

The Journal of Physical Chemistry Letters, Journal Year: 2024, Volume and Issue: unknown, P. 12129 - 12137

Published: Nov. 27, 2024

It is a critical and broad prospect to evaluate ion levels monitor their dynamic changes in the brain for early diagnosis, in-depth mechanism investigation, accurate staging of neurodegenerative diseases including Alzheimer's disease (AD). still great challenge vivo track Zn

Language: Английский

Citations

0