Terahertz scanning near-field optical microscopy for biomedical detection: Recent advances, challenges, and future perspectives DOI
Shihan Yan,

Guanyin Cheng,

Zhongbo Yang

et al.

Biotechnology Advances, Journal Year: 2024, Volume and Issue: unknown, P. 108507 - 108507

Published: Dec. 1, 2024

Language: Английский

Nanoscale Spatially Resolved Terahertz Response of a PbS-Graphene Heterostructure DOI
Fucheng Qiu, Shuanglong Feng,

Zhongbo Yang

et al.

ACS Nano, Journal Year: 2025, Volume and Issue: unknown

Published: March 11, 2025

Heterostructures have promising applications in photonics and optoelectronics, mainly due to their high electron mobility broadband photoresponse covering visible, infrared, terahertz (THz) ranges. However, it is challenging detect heterostructures definition with conventional THz techniques. Here we demonstrate a nanoscopic imaging method which capable of resolving the local response PbS-graphene based upon sophisticated near-field optical microscope. The interaction between near field heterostructure further explored by numerical simulations. results reveal that both composition structure layers composing contribute signal. Furthermore, develop reliably finite dipole model suitable for retrieving optoelectronic properties multilayered systems from measured hyperspectra, realize mapping effective permittivity conductivity heterostructure. Our work discloses mechanism heterostructures, provides useful high-definition quantifying complex materials devices.

Language: Английский

Citations

0

Single-Bacterium Diagnosis via Terahertz Near-Field Dielectric Nanoimaging DOI
Jie Zhou, Xiaoqiuyan Zhang, Xingxing Xu

et al.

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: March 12, 2025

Single-bacterium diagnostic methods with unprecedented precision and rapid turnaround times are promising tools for facilitating the transition from empirical treatment to personalized anti-infection treatment. Terahertz (THz) radiation, a cutting-edge technology identifying pathogens, enables label-free non-destructive detection of intermolecular vibrational modes bacterial dielectric properties. However, this individual property-based mismatched spatial resolution limited single-bacterium identification various species pathogens. Here, we demonstrate THz nanoimaging (STDN) strategy by customized scattering-type scanning near-field optical microscopy. The nanoimages bacteria explained confirmed theoretical modeling measurement. By synchronously tracking intrinsic property extrinsic morphology, achieved 99.3% 91.6% accuracy in antibiotic susceptibility testing trained classifier within 2 hours. This proof-of-concept STDN may propel precise infection management help counteract resistance.

Language: Английский

Citations

0

Sperm imaging utilizing terahertz near-field scanning microscopy DOI Creative Commons

Zhenchun Yu,

Chengyao Peng, Shun Bai

et al.

Biotechnology & Biotechnological Equipment, Journal Year: 2025, Volume and Issue: 39(1)

Published: April 14, 2025

Language: Английский

Citations

0

Terahertz scanning near-field optical microscopy for biomedical detection: Recent advances, challenges, and future perspectives DOI
Shihan Yan,

Guanyin Cheng,

Zhongbo Yang

et al.

Biotechnology Advances, Journal Year: 2024, Volume and Issue: unknown, P. 108507 - 108507

Published: Dec. 1, 2024

Language: Английский

Citations

0