Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics DOI Creative Commons
Jingyu Shi, Yadi Fan, Qin Zhang

et al.

Advanced Materials, Journal Year: 2025, Volume and Issue: unknown

Published: May 16, 2025

Abstract The rapidly advancing field of theranostics aims to integrate therapeutic and diagnostic functionalities into a single platform for precision medicine, enabling the simultaneous treatment monitoring diseases. Photo‐energy conversion‐based nanomaterials have emerged as versatile that utilizes unique properties light activate with high spatial temporal precision. This review provides comprehensive overview recent developments in photo‐energy conversion using nanomaterials, highlighting their applications disease theranostics. discussion begins by exploring fundamental principles including types materials used various light‐triggered mechanisms, such photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered SERS, photodynamic processes. Following this, delves broad spectrum emphasizing role diagnosis major diseases, cancer, neurodegenerative disorders, retinal degeneration, osteoarthritis. Finally, challenges opportunities technologies are discussed, aiming advance personalized medicine.

Language: Английский

Recent advances in photoelectrochemical detection of hydrogen sulfide DOI Creative Commons
Fang Chen, Xiuhua Wei, Yuanqiang Hao

et al.

International Journal of Electrochemical Science, Journal Year: 2025, Volume and Issue: unknown, P. 101046 - 101046

Published: April 1, 2025

Language: Английский

Citations

1

Electrochemically Active Materials for Tissue-Interfaced Soft Biochemical Sensing DOI
Xiaoyan Qian, Zehua Chen, Feng Zhang

et al.

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: April 21, 2025

Tissue-interfaced soft biochemical sensing represents a crucial approach to personalized healthcare by employing electrochemically active materials monitor signals at the tissue interface in real time, either noninvasively or through implantation. These sensors can be integrated with various biological tissues, such as neural, gastrointestinal, ocular, cardiac, skin, muscle, and bone, adapting their unique mechanical environments. Sensors like conductive polymers, composites, metals, metal oxides, carbon-based nanomaterials have demonstrated capabilities applications, continuous glucose monitoring, neural activity mapping, real-time metabolite detection, enhancing diagnostics treatment monitoring across range of medical fields. Next-generation tissue-interfaced biosensors that enable multimodal multiplexed measurement markers physiological parameters could transformative for medicine, allowing high-resolution, time-resolved historical an individual's health status. In this review, we summarize current trends field provide insights into challenges future trajectory sensors, highlighting potential revolutionize medicine improve patient outcomes.

Language: Английский

Citations

0

A Sensitive SERS Sensor for Simultaneous Detection of Two Potential Biomarkers of Alzheimer’s Disease: AChE and MAO-B DOI
Naifeng Yang, Xiaowan Zhang, Anran Liu

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: May 14, 2025

Monoamine oxidase B (MAO-B) and acetylcholinesterase (AChE) are potential biomarkers for Alzheimer's disease (AD). However, few methods exist to detect both AChE MAO-B simultaneously. In this study, we developed a SERS sensor the simultaneous detection of based on one-pot reaction system, which provided more valuable information early AD diagnosis. Au NPs modified with Raman reporter 4-aminothiophenol (AuPATP NPs) were attached Cu-BTC via Schiff's base NPs@Cu-BTC), resulting in great intensity. Phenethylamine (PEA), substrate MAO-B, competed AuPATP binding Cu-BTC, reducing intensity signal. Additionally, two PATP molecules free coupled DMAB due catalysis Cu2+ transforming into AuDMAB generating three new peaks. TCh, catalytic product AChE, was chelated Cu2+, so coupling efficiency has been decreased, conversion prevented. Based can be detected by signals from precipitated NPs@Cu-BTC supernatant after centrifugation. The limits 2.3 × 10-3 μg mL-1 1.6 U L-1 AChE. We successfully serum recoveries ranging 100.0 113.7% 93.6 120% This manuscript presents novel method showing

Language: Английский

Citations

0

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics DOI Creative Commons
Jingyu Shi, Yadi Fan, Qin Zhang

et al.

Advanced Materials, Journal Year: 2025, Volume and Issue: unknown

Published: May 16, 2025

Abstract The rapidly advancing field of theranostics aims to integrate therapeutic and diagnostic functionalities into a single platform for precision medicine, enabling the simultaneous treatment monitoring diseases. Photo‐energy conversion‐based nanomaterials have emerged as versatile that utilizes unique properties light activate with high spatial temporal precision. This review provides comprehensive overview recent developments in photo‐energy conversion using nanomaterials, highlighting their applications disease theranostics. discussion begins by exploring fundamental principles including types materials used various light‐triggered mechanisms, such photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered SERS, photodynamic processes. Following this, delves broad spectrum emphasizing role diagnosis major diseases, cancer, neurodegenerative disorders, retinal degeneration, osteoarthritis. Finally, challenges opportunities technologies are discussed, aiming advance personalized medicine.

Language: Английский

Citations

0