3d Transition Metals for C–H Activation

Chemical Reviews, Journal Year: 2018, Volume and Issue: 119(4), P. 2192 - 2452

Published: Nov. 27, 2018

C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with notable applications to material crop protection, drug discovery, and pharmaceutical industries, among others. Despite major advances, the vast majority of these functionalizations required precious 4d or 5d transition metal catalysts. Given cost-effective sustainable nature earth-abundant first row metals, development less toxic, inexpensive 3d catalysts gained considerable recent momentum a significantly more environmentally-benign economically-attractive alternative. Herein, we provide comprehensive overview on until summer 2018.

Language: Английский

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Metal–Organic Frameworks as Catalysts for Organic Synthesis: A Critical Perspective

Journal of the American Chemical Society, Journal Year: 2019, Volume and Issue: 141(18), P. 7223 - 7234

Published: April 11, 2019

Recent advances in organic chemistry and materials have enabled the porosity of new to be accurately controlled on nanometer scale. In this context, metal-organic frameworks (MOFs) rapidly become one most attractive classes solid supports currently under investigation heterogeneous catalysis. Their unprecedented degree tunability gives MOFs chance succeed where others failed. The past decade has witnessed an exponential growth complexity structures. with a variety topologies pore sizes show excellent stability across wide ranges pH temperature. Even insertion defects, alter MOF's properties predictable manner, commonplace. However, research catalysis been sluggish catching up modern trends chemistry. Relevant issues such as enantioselective processes, C-H activation, or olefin metathesis are still rarely discussed. Perspective, we highlight meritorious examples that tackle important from contemporary synthesis, provide fair comparison existing catalysts. Some these MOF catalysts already outcompete state-of-the-art homogeneous solutions. For others, improvements may required, but they merit aiming for bigger challenge. Furthermore, also identify some areas likely make difference, by addressing unmet needs instead trying excel. Finally, strongly advocate rational design catalysts, founded deep mechanistic understanding events taking place inside pore.

Language: Английский

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Additive manufacturing technology for porous metal implant applications and triple minimal surface structures: A review

Bioactive Materials, Journal Year: 2018, Volume and Issue: 4, P. 56 - 70

Published: Dec. 21, 2018

Recently, the fabrication methods of orthopedic implants and devices have been greatly developed. Additive manufacturing technology allows production complex structures with bio-mimicry features, has potential to overcome limitations conventional methods. This review explores open-cellular structural design for porous metal implant applications, in relation mechanical properties, biocompatibility, biodegradability. Several types additive techniques including selective laser sintering, melting, electron beam are discussed different applications. through powder bed fusion shows great high-quality implants. However, technique still faces two major challenges: it is high cost time-consuming. In addition, triply periodic minimal surface (TPMS) also analyzed this paper, targeting an enhanced biomorphic environment.

Language: Английский

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Using nature’s blueprint to expand catalysis with Earth-abundant metals

Science, Journal Year: 2020, Volume and Issue: 369(6505)

Published: Aug. 14, 2020

Making chemistry less precious Much of modern relies on catalysis by metals such as platinum, palladium, and rhodium. By contrast, more abundant iron copper suffice in biochemistry. Bullock et al. review the opportunities presented from study enzymes to shift balance synthetic catalysts further toward use these metals. Whether modifying themselves or designing ligand support architectures that take advantage cheaper metals' characteristic electron transfer properties, recent work points substantial progress. Science , this issue p. eabc3183

Language: Английский

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C–H activation

Nature Reviews Methods Primers, Journal Year: 2021, Volume and Issue: 1(1)

Published: June 17, 2021

Language: Английский

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Assessment of heavy metal pollution and human health risks in urban soils around an electronics manufacturing facility

The Science of The Total Environment, Journal Year: 2018, Volume and Issue: 630, P. 53 - 61

Published: Feb. 20, 2018

Language: Английский

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Computational Approach to Molecular Catalysis by 3d Transition Metals: Challenges and Opportunities

Chemical Reviews, Journal Year: 2018, Volume and Issue: 119(4), P. 2453 - 2523

Published: Oct. 30, 2018

Computational chemistry provides a versatile toolbox for studying mechanistic details of catalytic reactions and holds promise to deliver practical strategies enable the rational in silico catalyst design. The reactivity nontrivial electronic structure effects, common systems based on 3d transition metals, introduce additional complexity that may represent particular challenge standard computational strategies. In this review, we discuss challenges capabilities modern methods reaction mechanisms promoted by metal molecular catalysts. Particular focus will be placed ways addressing multiconfigurational problem calculations role expert bias utilization available methods. development density functionals designed address metals is also discussed. Special emphasis account solvation effects multicomponent nature systems. This followed an overview recent studies processes catalysts metals. Cases involve noninnocent ligands, systems, metal-ligand metal-metal cooperativity, as well modeling complex such metal-organic frameworks are presented. Conventionally, heavily dependent chemical intuition input researcher. Recent developments advanced automated path analysis hold eliminating human-bias from catalysis studies. A brief these approaches presented final section review. paper closed with general concluding remarks.

Language: Английский

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Biobased polyurethanes for biomedical applications

Bioactive Materials, Journal Year: 2020, Volume and Issue: 6(4), P. 1083 - 1106

Published: Oct. 15, 2020

Polyurethanes (PUs) are a major family of polymers displaying wide spectrum physico-chemical, mechanical and structural properties for large range fields. They have shown suitable biomedical applications used in this domain since decades. The current variety biomass available has extended the diversity starting materials elaboration new biobased macromolecular architectures, allowing development PUs with advanced such as controlled biotic abiotic degradation. In frame, tunable devices been successfully designed. PU structures precise tissue biomimicking can be obtained adequate adhesion, proliferation differentiation many cell's types. Moreover, smart shape-memory adjustable shape-recovery demonstrated promising results wound healing. fossil-based substitution implants is slowly improving, nonetheless better renewable contents need to achieved most obtain certifications. After presentation some generalities an understanding biomaterial structure-biocompatibility relationship, recent developments non-implantable well short- long-term described detail review compared more conventional structures.

Language: Английский

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A Pharmaceutical Industry Perspective on Sustainable Metal Catalysis

Organometallics, Journal Year: 2018, Volume and Issue: 38(1), P. 36 - 46

Published: Oct. 4, 2018

As companies grow ever more mindful of the sustainability aspects their products and supply chains, an increasing focus on environmental impact pharmaceutical manufacture spurs innovation from chemists who support this industry. Metal catalysis has potential to greatly enhance products, leading shorter efficient synthetic routes direct access single stereoisomeric products. This perspective article seeks highlight a number important considerations for design new improved sustainable metal-catalyzed transformations in order facilitate rapid adoption by

Language: Английский

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Organic synthesis with the most abundant transition metal–iron: from rust to multitasking catalysts

Chemical Society Reviews, Journal Year: 2021, Volume and Issue: 50(1), P. 243 - 472

Published: Jan. 1, 2021

The promising aspects of iron in synthetic chemistry are being explored for three-four decades as a green and eco-friendly alternative to late transition metals. This present review unveils these rich iron-chemistry towards different transformations.

Language: Английский

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