Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(31), P. 5911 - 5915
Published: Aug. 2, 2023
An
unprecedented
Csp3-H
imination
reaction
using
arylazo
sulfones
as
the
readily
accessible
and
stable
N
source
is
reported.
The
synthetic
virtues
are
demonstrated
through
mild
conditions,
simple
operation,
good
air
compatibility,
functional
group
tolerance,
well
suitability
for
gram-scale
reaction.
resulting
imines
can
be
further
converted
to
α-amino
acids.
presented
results
shed
light
on
an
unusual
usage
of
will
inspire
novel
experimental
design
by
source.
Reactions,
Journal Year:
2024,
Volume and Issue:
5(3), P. 492 - 566
Published: Aug. 16, 2024
The
present
review
is
a
comprehensive
update
of
the
synthesis
monocyclic
β-lactams
via
cycloaddition
reactions.
According
to
IUPAC
definition
cycloaddition,
both
elementary
and
stepwise
processes
(formal
cycloadditions)
have
been
considered.
years
2019–2022
are
covered
by
cited
literature.
focus
on
synthetic
aspects
with
emphasis
structural
scope,
reaction
conditions,
mechanistic
aspects,
selectivity
results.
Selected
significant
data
related
biological
activities
applications
also
highlighted.
Advanced Synthesis & Catalysis,
Journal Year:
2024,
Volume and Issue:
366(22), P. 4548 - 4558
Published: Oct. 8, 2024
Abstract
The
synthesis
of
β‐lactam
scaffolds
is
paramount
importance
due
to
their
extensive
applications
in
pharmaceuticals,
particularly
as
antibiotics.
Visible
light
photocatalysis
has
emerged
a
revolutionary
approach
this
domain,
providing
sustainable
and
efficient
pathway
for
construction.
In
review,
we
meticulously
discuss
the
recent
developments
photocatalysed
frameworks.
A
key
focus
Staudinger
reaction,
traditionally
cornerstone
synthesis,
its
adaptation
visible
photocatalysis.
We
explore
mechanistic
intricacies
reaction
under
photochemical
conditions,
along
with
other
pivotal
cyclization
strategies
enabled
by
light.
By
illuminating
novel
photocatalytic
routes
β‐lactams,
review
provides
thorough
understanding
state‐of‐the‐art
techniques
sets
stage
future
innovations
green
these
critical
compounds.
The Journal of Organic Chemistry,
Journal Year:
2022,
Volume and Issue:
87(24), P. 16492 - 16505
Published: Dec. 6, 2022
A
convenient
method
was
developed
for
the
preparation
of
thiolated
compounds
via
a
DBU-catalyzed
aerobic
cross-dehydrogenative
coupling
(CDC)
reaction.
The
established
protocol
is
environmentally
friendly
and
operationally
simple.
Substrates
like
(hetero)aryl
acetates,
ketones,
indoles
could
be
transformed
into
corresponding
products
in
moderate
to
high
yields
further
applied
bioactive
prefunctionalization-free
manner.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(31), P. 5911 - 5915
Published: Aug. 2, 2023
An
unprecedented
Csp3-H
imination
reaction
using
arylazo
sulfones
as
the
readily
accessible
and
stable
N
source
is
reported.
The
synthetic
virtues
are
demonstrated
through
mild
conditions,
simple
operation,
good
air
compatibility,
functional
group
tolerance,
well
suitability
for
gram-scale
reaction.
resulting
imines
can
be
further
converted
to
α-amino
acids.
presented
results
shed
light
on
an
unusual
usage
of
will
inspire
novel
experimental
design
by
source.
