Acta Crystallographica Section E Crystallographic Communications,
Journal Year:
2023,
Volume and Issue:
79(7), P. 633 - 636
Published: June 13, 2023
The
title
compound,
1-(4-bromo-phen-yl)but-3-yn-1-one,
C10H7BrO,
crystallizes
in
the
monoclinic
space
group
P21/n
with
one
mol-ecule
asymmetric
unit.
structure
displays
a
planar
geometry.
crystal
is
consolidated
by
C-H⋯O
hydrogen
bonding
and
short
C=O⋯C≡C
(acetyl-ene)
contacts.
Hirshfeld
surface
analysis
indicates
that
H⋯H,
C⋯H/H⋯C
H⋯Br/Br⋯H
inter-actions
play
more
important
role
consolidating
compared
to
H⋯O/O⋯H
C⋯C
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(1), P. 215 - 219
Published: Jan. 3, 2023
An
unprecedented
annulation
reaction
is
developed
for
the
synthesis
of
dihydrofuran-fused
compounds.
In
this
Ru-catalyzed
hydroxyl-group-directed
reaction,
easily
affordable
sulfoxonium
ylides
and
1,4-dioxane
were
used
as
annulating
partners.
This
first
example
use
a
methylene
source
to
construct
heterocyclic
scaffold.
A
wide
range
dihydrofuran0fused
coumarins
naphthalenes
synthesized
using
three-component
reaction.
Advanced Synthesis & Catalysis,
Journal Year:
2023,
Volume and Issue:
365(9), P. 1457 - 1464
Published: April 14, 2023
Abstract
In
this
study,
Rh(III)‐catalyzed
C−H
bifunctionalization
and
direct
vinylene
annulation
of
sulfoxonium
ylides
N
‐carbamoylindoles
with
carbonate
was
accomplished,
which
afforded
a
series
naphthalenones
containing
β‐ketosulfoxonium
ylide
moiety,
isocoumarins,
pyrimidones.
This
protocol
featured
mild
conditions,
broad
substrate
scope,
functional‐groups
compatibility.
addition,
related
applications
preliminary
mechanistic
exploratory
were
also
investigated
magnified
image
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(11), P. 2249 - 2254
Published: March 7, 2024
A
copper-mediated
[3
+
2]
cyclization
of
CF3-imidoyl
sulfoxonium
ylides
and
terminal
alkynes
has
been
demonstrated.
This
work
provides
a
practical
approach
for
assembling
5-trifluoromethylpyrroles
with
the
merits
broad
substrate
scope,
good
functional
tolerance,
mild
reaction
conditions.
Control
experiments
DFT
studies
indicate
that
this
may
involve
addition
π-bonds
by
copper-carbene
radicals
hydrogen
migration.
Organic & Biomolecular Chemistry,
Journal Year:
2023,
Volume and Issue:
21(14), P. 2842 - 2869
Published: Jan. 1, 2023
The
1,3-diynes
hold
a
prominent
position
among
the
many
coupling
partners
employed
in
metal-catalysed
C–H
activation
because
of
their
ability
to
form
complex
bis-heterocycles
one
shot.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(19), P. 3352 - 3357
Published: May 4, 2023
Rh-catalyzed
weak
and
traceless
directing-group-assisted
cascade
C–H
activation
annulation
of
sulfoxonium
ylides
with
vinyl
cyclopropanes
as
a
coupling
partner
have
been
accomplished
to
furnish
functionalized
cyclopropane-fused
tetralones
at
moderate
temperature.
The
C–C
bond
formation,
cyclopropanation,
functional
group
tolerance,
late-stage
diversifications
drug
molecules,
scale-up
are
the
important
practical
features.
The Journal of Organic Chemistry,
Journal Year:
2022,
Volume and Issue:
87(21), P. 13757 - 13762
Published: Oct. 25, 2022
Herein,
we
disclose
an
efficient
ruthenium-catalyzed
C–H
functionalization
of
2-arylbenzimidazoles/2-arylimidazoles
with
iodonium
ylides
leading
to
substituted
tetracyclic
and
pentacyclic
bridgehead
N-heterocycles,
wherein
ylide
acts
as
a
carbene
precursor.
For
the
first
time,
proceeds
through
Ru–carbenoid
intermediate.
Further,
synthetic
utility
this
protocol
was
successfully
shown
for
gram-scale
synthesis
useful
transformations.
Organic Letters,
Journal Year:
2022,
Volume and Issue:
24(30), P. 5624 - 5628
Published: July 27, 2022
A
palladium
catalyzed
dicarbonylation
of
α-iodo-substituted
ACPs
for
the
synthesis
carbamoyl
substituted
indenones
has
been
developed.
Two
carbonyl
groups
were
incorporated
into
product
with
cleavage
proximal
C-C
bond
ACPs.
broad
range
efficiently
prepared
in
good
to
excellent
yields.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(39), P. 7148 - 7153
Published: Sept. 26, 2023
A
[Cp*IrCl2]2-catalyzed
amidocarbonation
of
olefins
with
sulfoxonium
ylides
has
been
developed
to
generate
diverse
biologically
important
isoindolin-1-ones
in
high
efficiency
under
mild
reaction
conditions.
Mechanism
studies
indicated
that
this
cascade
was
triggered
by
amino-iridation
the
olefin
unit
iridacycle,
followed
formal
migratory
insertion
ylides.
This
newly
method
features
broad
substrate
scopes
and
operational
simplicity.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(25), P. 4615 - 4620
Published: June 21, 2023
A
novel
palladium(II)-catalyzed
intramolecular
[2
+
2
2]
annulation
of
indolyl
1,3-diynes
is
described
in
this
contribution.
variety
azepino-fused
carbazoles
are
obtained
moderate
to
excellent
yields.
The
key
the
success
transformation
use
a
carboxylic
acid
as
an
additive.
This
protocol
features
broad
functional
group
tolerances,
easy
handling
air,
and
100%
atom
economy.
Furthermore,
scale-up
reactions,
late-stage
derivatizations,
photophysical
property
investigations
highlight
potential
synthetic
utility
methodology.
