Chinese Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
43(11), P. 3939 - 3939
Published: Jan. 1, 2023
Alkyl
aryl
ketones
are
a
class
of
valuable
compounds
in
chemistry
and
biology,
which
widely
used
the
pharmaceutical,
spice,
dye,
pesticide,
functional
materials,
organic
synthesis
industries.A
cobalt-catalyzed
oxyalkylation
reaction
olefin
with
tert-butyl
hydroperoxide
(TBHP)
cyclic
ethers
was
developed.Various
substrates
electron-withdrawing
or
electron-donating
groups
were
tolerated
this
protocol
to
provide
α-alkyl
substituted
acetophenones
moderate
yields.The
present
features
broad
substrate
scope,
flexibility,
allowing
rapid
assembly
series
value-added
acetophenone
derivatives
under
mild
conditions
good
efficacy.
Molecules,
Journal Year:
2023,
Volume and Issue:
28(6), P. 2729 - 2729
Published: March 17, 2023
Ferrocenium
catalysis
is
a
vibrant
research
area,
and
an
increasing
number
of
ferrocenium-catalyzed
processes
have
been
reported
in
the
recent
years.
However,
ferrocenium
cation
not
very
stable
solution,
which
may
potentially
hamper
catalytic
applications.
In
effort
to
stabilize
ferrocenium-type
architectures
by
inserting
bridge
between
cyclopentadienyl
rings,
we
investigated
two
ferrocenophanium
(or
ansa-ferrocenium)
cations
with
respect
their
stability
activity
propargylic
substitution
reactions.
One
complexes
was
characterized
single
crystal
X-ray
diffraction.
Cyclic
voltammetry
experiments
ferrocenophane
parent
compounds
were
performed
absence
presence
alcohol
nucleophiles,
solution
judged
based
on
reversibility
electron
transfer.
The
revealed
moderate
stabilizing
effect
bridge,
albeit
pronounced
or
straightforward.
Catalytic
test
reactions
decreased
compared
cation.
It
appears
that
somewhat
stabilized
show
activity.
Angewandte Chemie,
Journal Year:
2023,
Volume and Issue:
135(25)
Published: April 22, 2023
Abstract
In
this
study,
we
designed
a
bilateral
disulfurating
reagent
via
S−S
motif
“snip
and
stitch”
processes,
allowing
diverse
functional
groups
to
be
bridged
bonds.
The
is
readily
synthesized
in
high
yield
using
one‐step
reaction
from
easily
available
starting
materials
air‐stable.
With
reagent,
electrophiles
including
inactivated
alkyl
Cl/Br/I/OMs
benzyl
chloride
were
sequentially
installed
on
either
side
of
the
motif.
Natural
products,
agrochemicals,
pharmaceuticals
can
successively
cross‐linked
with
Notably,
used
cyclic
disulfide
synthesis.
At
last,
some
desired
products
work
showed
good
antibacterial
activities,
which
could
employed
as
novel
candidates
control
plant
pathogenic
bacteria.
Chinese Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
43(11), P. 3939 - 3939
Published: Jan. 1, 2023
Alkyl
aryl
ketones
are
a
class
of
valuable
compounds
in
chemistry
and
biology,
which
widely
used
the
pharmaceutical,
spice,
dye,
pesticide,
functional
materials,
organic
synthesis
industries.A
cobalt-catalyzed
oxyalkylation
reaction
olefin
with
tert-butyl
hydroperoxide
(TBHP)
cyclic
ethers
was
developed.Various
substrates
electron-withdrawing
or
electron-donating
groups
were
tolerated
this
protocol
to
provide
α-alkyl
substituted
acetophenones
moderate
yields.The
present
features
broad
substrate
scope,
flexibility,
allowing
rapid
assembly
series
value-added
acetophenone
derivatives
under
mild
conditions
good
efficacy.
