Remote C(sp3)–H heteroarylation of N-fluoroarylsulfonamides via a silyl radical process under visible light irradiation DOI
Ya‐Jian Hu, Jinchang Liu, Guangyi Zhang

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(18), P. 5016 - 5025

Published: Jan. 1, 2024

An efficient method for the remote heteroarylation of unactivated C(sp 3 )–H bonds has been developed involving a silyl radical-mediated relay reaction.

Language: Английский

CAr–Br bond cleavage via cooperative EnT/NHC catalysis: mild access to indolines DOI

Yi-Xiong Dong,

Cao‐Bo Li,

Ming‐Lei Jin

et al.

Science China Chemistry, Journal Year: 2023, Volume and Issue: 67(3), P. 922 - 927

Published: Dec. 8, 2023

Language: Английский

Citations

3
DFT study on stereoselective Rh-catalyzed intramolecular [2 + 2 + 2] cycloaddition of allene–ene–ynes DOI
Xinrui Zhu, De‐Cai Fang

Organic Chemistry Frontiers, Journal Year: 2023, Volume and Issue: 10(11), P. 2624 - 2634

Published: Jan. 1, 2023

CAT catalyzes the reaction of 1a to generate intermediate INT2, which is a common final products 2a and 3a.

Language: Английский

Citations

2
Cooperative Carbene Photocatalysis for B-Amino Ester Synthesis DOI Creative Commons
Nao Tanaka,

Josh Zhu,

Oniya L. Valencia

et al.

Published: Sept. 11, 2023

B-Amino acids are useful building blocks of bioactive molecules, including peptidomimetics and pharmaceutical compounds. The current limited accessibility to B-2,2-type amino which bear an a-quaternary center has their use in chemical synthesis biological investigations. Disclosed herein is the development a new N-heterocyclic carbene/photocatalyzed aminocarboxylation olefins, affording B-2,2-amino esters with high regioselectivity. generation nitrogen-centered radicals derived from simple imides via se-quence deprotonation single-electron oxidation allows for subsequent addition gem-disubstituted olefins regioselectively. intermediate tertiary then cross-couple stabilized azolium-based radical generated situ efficiently construct quaternary centers. Mechanistic studies Stern-Volmer fluorescence quenching experiments support proposed catalytic cycle.

Language: Английский

Citations

2
遠隔位電子チューニングによるN-複素環式カルベン触媒の高性能化 DOI
Tsubasa Inokuma, Ken‐ichi Yamada

Journal of Synthetic Organic Chemistry Japan, Journal Year: 2024, Volume and Issue: 82(3), P. 222 - 233

Published: March 1, 2024

One of the privileged motifs chiral N-heterocyclic carbene (NHC) catalyst is an aminoindanol-derived structure, and many researchers achieved improvement this type by introducing various substitutions at triazolium nitrogen, which located proximal site reactive carbene. Recently, we found that introduction substituents benzene ring indane moiety, far from carbon, could efficiently tune catalytic activity NHC catalysts in enantioselective acylation racemic alcohols, asymmetric intramolecular Stetter reactions, intermolecular benzoin condensation benzaldehyde derivatives. Herein, report development novel high-performance remote substituent effects.

Language: Английский

Citations

0
Remote C(sp3)–H heteroarylation of N-fluoroarylsulfonamides via a silyl radical process under visible light irradiation DOI
Ya‐Jian Hu, Jinchang Liu, Guangyi Zhang

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(18), P. 5016 - 5025

Published: Jan. 1, 2024

An efficient method for the remote heteroarylation of unactivated C(sp 3 )–H bonds has been developed involving a silyl radical-mediated relay reaction.

Language: Английский

Citations

0