Recent Advance in the Synthesis of Ullazine and Its Derivatives DOI

Zimeng Shao,

Yuanhui Wang,

Haiying Wang

et al.

Chinese Journal of Organic Chemistry, Journal Year: 2023, Volume and Issue: 43(11), P. 3679 - 3679

Published: Jan. 1, 2023

Language: Английский

Recent Advances in the Synthesis of Fused‐Cyclic Quinolines DOI

Shahab A. Darbandizadeh,

Saeed Balalaie

Asian Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 13(5)

Published: Feb. 16, 2024

Abstract Fused quinolines have gained substantial attention due to their significant biological and wide‐spectrum synthetic applications. This review supplies an encyclopedic document regarding the approaches developed for synthesis of fused‐cyclic based on ring volume size reported thus far. collected information will be valuable medicinal chemists obtain knowledge designing new in order access active compounds.

Language: Английский

Citations

6
Regio‐ and Chemoselective Formal (4+1) Carbocyclization of Chalcones with Internal Alkynes via Rhodium(III) Catalysis DOI Open Access

Shuaishuai Song,

Yunfei Lai,

Zekun Tuo

et al.

Angewandte Chemie International Edition, Journal Year: 2023, Volume and Issue: 62(30)

Published: May 23, 2023

Abstract A rhodium(III)‐catalyzed oxidative cyclization of chalcones with internal alkynes is reported, generating biologically important 3,3‐disubstituted 1‐indanones along reusable aromatic aldehydes. This transformation features unique (4+1) reaction mode, excellent regioselectivity in alkyne insertion, broad substrate scope, allows for the construction quaternary carbon centers, and scalable. Steric hindrance from ligand probably controls chemoselectivity this carbocyclization. Importantly, discovery enables a practical two‐step protocol switching overall acetophenones (3+2) to annulation.

Language: Английский

Citations

9
Benzofuranone-based spiropyrans: synthesis, temperature-dependent photochromic properties, and DFT calculations DOI
Xinjie Zhou, Zhenyu Chang,

Yongchun Hu

et al.

Organic Chemistry Frontiers, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

The synthesis of benzofuranone-based spiropyrans containing a thiophene, benzothiophene, or indole moiety, their diverse temperature-dependent photochromic properties, and DFT rationalization.

Language: Английский

Citations

0
Synthesis of Nitrogen-Containing Heterocyclic Scaffolds through Sequential Reactions of Aminoalkynes with Carbonyls DOI Creative Commons
Antonio Arcadi, Valerio Morlacci, Laura Palombi

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(12), P. 4725 - 4725

Published: June 12, 2023

Sequential reactions of aminoalkynes represent a powerful tool to easily assembly biologically important polyfunctionalized nitrogen heterocyclic scaffolds. Metal catalysis often plays key role in terms selectivity, efficiency, atom economy, and green chemistry these sequential approaches. This review examines the existing literature on applications with carbonyls, which are emerging for their synthetic potential. Aspects concerning features starting reagents, catalytic systems, alternative reaction conditions, pathways possible intermediates provided.

Language: Английский

Citations

5
Synthesis of Nitrogen Containing Heterocyclic Scaffolds through Sequential Reactions of Aminoalkynes with Carbonyls DOI Open Access
Antonio Arcadi, Valerio Morlacci, Laura Palombi

et al.

Published: May 17, 2023

Sequential reactions of aminoalkynes represent a powerful tool to easily assembly biologically important polyfunctionalized nitrogen heterocyclic scaffolds. Metal catalysis often plays key role in terms selectivity, efficiency, atom economy and green chemistry these sequential approaches. This review examines the existing literature on applications with carbonyls which are emerging for their synthetic potential. Aspect concerning features starting reagents, catalytic systems, alternative reaction conditions pathways as well possible intermediates provided.

Language: Английский

Citations

4
1,3‐Dipolar Cycloaddition of Polycyclic Aromatic Azomethine Ylides and Alkynylbenziodoxoles for Synthesis of Functional Dibenzoullazines† DOI

Hui Han,

Glen Wee Zhuan Goh,

Yongxin Li

et al.

Chinese Journal of Chemistry, Journal Year: 2024, Volume and Issue: 42(10), P. 1079 - 1083

Published: Jan. 23, 2024

Comprehensive Summary A new family of dibenzoullazine derivatives was synthesized through 1,3‐dipolar cycloaddition polycyclic aromatic azomethine ylides with alkynylbenziodoxoles followed by oxidation. The benziodoxole moiety in the resulting products used as a versatile linchpin for synthesis structurally diverse functional dibenzoullazines that are difficult to access other synthetic methods.

Language: Английский

Citations

1
One‐Pot Rh(III)‐Catalyzed Twofold C−H Activation/Oxidative Annulation of N‐Arylpyrroles with Alkynes to Fluorescent Ullazines DOI Creative Commons

Sergio Otero‐Riesgo,

Jesús A. Varela, Carlos Saá

et al.

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: 366(10), P. 2312 - 2323

Published: March 28, 2024

Abstract A range of densely functionalized ullazines have been synthesized by a one‐pot Rh(III)‐catalyzed twofold C−H activation/oxidative annulation N ‐arylpyrroles with alkynes. Electrophilic bromination at 5‐ or 5,7‐ positions the EWG‐substituted ullazine core offers an interesting single double entry for further extended functionalization. Mechanistic considerations suggest two complementary paths, EWG‐assisted and S E Ar, activations. All exhibit strong fluorescence emissions. Ullazines bearing thiophene triarylamine units show significant bathochromic shift in their emission spectra, attributed to more electronic circuits present.

Language: Английский

Citations

1
Aza-dicyclopenta[a,g]naphthalenes: controllable seesaw-like emissive behavior and narrowband AIEgens DOI Creative Commons

Jinbiao Li,

Jiaxin Lao, Hongbin Zou

et al.

Chemical Science, Journal Year: 2023, Volume and Issue: 14(40), P. 11203 - 11212

Published: Jan. 1, 2023

An aza-dicyclopenta[ a , g ]naphthalene scaffold was discovered as controllable luminogenic structure, and precise balance of molecular motions unlocks the remarkable narrowband AIEgens.

Language: Английский

Citations

1
Synthesis of pyrrolo[1,2-a]quinoline and pyrrolo[1,2-b]isoquinoline derivatives via intramolecular acylation DOI

Yingying Zhai,

Guodong Hou,

Chengxiang Yi

et al.

Tetrahedron, Journal Year: 2024, Volume and Issue: 166, P. 134224 - 134224

Published: Aug. 30, 2024

Language: Английский

Citations

0
Regio‐ and Chemoselective Formal (4+1) Carbocyclization of Chalcones with Internal Alkynes via Rhodium(III) Catalysis DOI Open Access

Shuaishuai Song,

Yunfei Lai,

Zekun Tuo

et al.

Angewandte Chemie, Journal Year: 2023, Volume and Issue: 135(30)

Published: May 23, 2023

Abstract A rhodium(III)‐catalyzed oxidative cyclization of chalcones with internal alkynes is reported, generating biologically important 3,3‐disubstituted 1‐indanones along reusable aromatic aldehydes. This transformation features unique (4+1) reaction mode, excellent regioselectivity in alkyne insertion, broad substrate scope, allows for the construction quaternary carbon centers, and scalable. Steric hindrance from ligand probably controls chemoselectivity this carbocyclization. Importantly, discovery enables a practical two‐step protocol switching overall acetophenones (3+2) to annulation.

Language: Английский

Citations

0