European Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
27(47)
Published: Sept. 13, 2024
Abstract
A
well‐ordered
strategy
of
sulfoxonium
ylides
as
a
directing
group
well
carbene
source
for
the
Ru‐catalysed
[4+2]
and
Rh‐catalysed
[4+1]
carbo‐annulations
with
maleimides
has
been
described.
These
novel
methodologies
have
successfully
established
synthesis
complex
spiroindanones
benzoisoindoles
containing
compounds
by
transition
metal‐mediated
C−H
activation/functionalization
reactions.
Further,
annulated
were
obtained
in
absence
any
oxidant.
possible
rationale
remarkable
divergent
selectivity
between
two
catalysts
proposed.
Chemical Communications,
Journal Year:
2024,
Volume and Issue:
60(16), P. 2125 - 2136
Published: Jan. 1, 2024
In
this
feature
article,
we
focus
on
the
photochemical
strategy
for
construction
of
heterocyclic
skeletons,
specifically
highlighting
methods
that
employ
visible
light-promoted
carbene
transfer
reactions.
Chemical Society Reviews,
Journal Year:
2024,
Volume and Issue:
53(10), P. 4926 - 4975
Published: Jan. 1, 2024
In
search
for
the
perfect
wave(length).
This
review
is
dedicated
to
recent
efforts
in
development
of
visible
light
driven
photochemical
strategies
occurring
coloured
organic
compounds.
Chemical Society Reviews,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
This
review
aims
to
provide
an
overview
of
radical
Brook
rearrangement,
which
is
organized
by
grouping
three
type
reactive
species
generated
via
the
unique
rearrangement
process.
Chemistry - An Asian Journal,
Journal Year:
2024,
Volume and Issue:
19(11)
Published: April 11, 2024
A
mild
protocol
for
hydroacylation
of
enones
through
photosensitization
acyl
silanes
with
thioxanthone
under
blue
light
(455
nm)
irradiation
is
reported.
Brønsted
acid
used
as
a
cocatalyst
in
the
reaction.
The
versatility
method
demonstrated
inter-
and
intramolecular
product
applied
synthesizing
an
anti-HCV
agent.
Mechanistic
insights
are
also
provided
control
experiments.
The Journal of Organic Chemistry,
Journal Year:
2025,
Volume and Issue:
90(4), P. 1727 - 1732
Published: Jan. 20, 2025
The
insertion
of
carbene
into
secondary
amide
N-H
bonds
remains
underexplored
in
organic
synthesis.
In
this
work,
we
discovered
the
visible-light-induced
siloxycarbene
bonds.
This
metal-free,
facile
reaction
proceeds
with
atom
economy
under
mild
conditions
a
broad
range
amides,
including
benzanilide,
acetanilide,
oxindole,
isatin,
quinolinone,
and
maleimide,
affording
stable
N-
O-acetals
excellent
isolated
yields.
addition,
chemoselective
reveals
robustness
chemical
transformation.
Advanced Synthesis & Catalysis,
Journal Year:
2024,
Volume and Issue:
366(19), P. 4139 - 4144
Published: July 2, 2024
Abstract
A
copper‐catalyzed
annulation
of
enaminones
with
maleimides
was
developed
to
synthesize
various
pyrrolo[3,4‐e]isoindoles.
In
this
strategy,
2‐aminopyridine
served
as
a
traceless
directing
group,
and
target
products
were
obtained
in
54–72%
yields.
Moreover,
plausible
mechanism
for
reaction
proposed
based
on
several
control
experiments,
deuterium
exchange
previous
reports.
The Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
88(19), P. 14205 - 14209
Published: Sept. 22, 2023
Acylsilanes
are
able
to
react
as
nucleophilic
carbene
precursors,
electrophiles,
and
directing
groups
in
C–H
functionalization.
To
date,
some
of
the
products
reportedly
formed
during
transition-metal-catalyzed
photochemical
reactions
involving
acylsilanes
have
been
incorrectly
assigned.
provide
clarity,
we
herein
address
these
structural
misassignments
detail
revised
structures.
New
insights
into
reactivity
were
also
afforded
via
discovery
that
light-induced
siloxy
carbenes
participate
intramolecular
1,2-carbonyl
addition
proximal
esters.
The Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
88(23), P. 16229 - 16247
Published: Nov. 15, 2023
Herein,
we
report
an
efficient
[3
+
2]
annulation
of
ortho-substituted
iodoarenes
with
maleimides
via
a
palladium-catalyzed
consecutive
double
Heck-type
strategy,
leading
to
fused
tricyclic
frameworks
pharmaceutical
relevance.
The
protocol
ensued
through
inter-
and
intramolecular
Heck
couplings
effectively.
This
approach
was
compatible
large
variety
substrates
functional
groups,
it
remarkably
tolerated
unprotected
maleimide.
