Copper-Catalyzed Cascade Cyclization of 2-Nitrochalcones with NH-Heterocycles DOI
Thang M. Ly, Tan N. Huynh, Nam Phan

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 19, 2024

We developed a method for allowing cascade cyclization of 2-nitrochalcones with pyrazoles, imidazole, and indazole in the presence CuI catalyst, DBU base, THF solvent. The conditions were tolerant an array useful functionalities including ester, nitro, cyano, halogen groups. A mechanistic consideration was also provided, as H2O2 presumably byproduct. Our appears to be rare example directly prepare C3-heterocyclic unprotected indoles.

Language: Английский

Synthesis of tetrasubstituted selenophenes by DBU-induced sequential three-component coupling and intramolecular cyclization DOI
Xiaoyu Wang, Kelu Yan, Jiangwei Wen

et al.

New Journal of Chemistry, Journal Year: 2023, Volume and Issue: 47(43), P. 19822 - 19826

Published: Jan. 1, 2023

A DBU-promoted three-component cascade annulation of 3-oxo-3-phenylpropanenitriles, ( E )-chalcones and selenium powder has been proposed for the synthesis tetrasubstituted selenophenes.

Language: Английский

Citations

1
One‐Pot Three‐Component Construction of 2,4‐Diarylbenzo[4,5] thieno[3,2‐d] pyrimidines Using Elemental Sulfur as a Sulfur Source DOI
Guorui Li, Fei Wen, Zheng Li

et al.

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(23)

Published: June 18, 2024

Abstract An efficient method for the construction of 2,4‐diarylbenzo[4,5]thieno[3,2‐ d ]pyrimidines through base‐promoted one‐pot three‐component tandem reactions o ‐nitrochalcones, benzamidine hydrochlorides, and elemental sulfur is described. The salient features this protocol are use cheap abundant source, readily available starting materials, transition‐metal‐free mild conditions, satisfactory yield, simple workup procedures. This transformation can also carry out on gram scale.

Language: Английский

Citations

0
Multicomponent synthesis of functionalized pyrrolo[3,4-e]isoindole-1,3,6,8-tetraones via [2 + 2 + 2] cycloaddition of maleimides with nitroenamines DOI

Jia-Ming Yang,

Bi-Na Shao,

Xing-Mei Hu

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(21), P. 6144 - 6149

Published: Jan. 1, 2024

We developed a protocol for the synthesis of PIITOs from maleimides and nitroenamines. This strategy featured [2 + 2 2] cycloaddition with heating mixture substrates 1 DMF without any catalyst.

Language: Английский

Citations

0
Six-membered ring systems: Diazines and benzo derivatives DOI

K. Alison Rinderspacher

Progress in heterocyclic chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 355 - 393

Published: Jan. 1, 2024

Citations

0
Copper-Catalyzed Cascade Cyclization of 2-Nitrochalcones with NH-Heterocycles DOI
Thang M. Ly, Tan N. Huynh, Nam Phan

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 19, 2024

We developed a method for allowing cascade cyclization of 2-nitrochalcones with pyrazoles, imidazole, and indazole in the presence CuI catalyst, DBU base, THF solvent. The conditions were tolerant an array useful functionalities including ester, nitro, cyano, halogen groups. A mechanistic consideration was also provided, as H2O2 presumably byproduct. Our appears to be rare example directly prepare C3-heterocyclic unprotected indoles.

Language: Английский

Citations

0