Iridium(III)-catalyzed remote B(9)−H alkylation of o-carboranes with nitrile template DOI Creative Commons
Phil Ho Lee, Kyungsup Lee, Ji‐Won Kim

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: July 24, 2024

Abstract Although the directing group assisted ortho-B − H activation reactions of o-carboranes have been well established during past decade, meta-B are unexplored so far. Herein, iridium(III)-catalyzed remote B(9) alkylation with nitrile template demonstrated for first time. It was revealed that fine tuning structures is essential high reaction efficiency and regioselectivity. This process exhibits a broad substrate scope good functional tolerance under simple conditions. The template, readily accessible from o-carborane acids, can be removed conveniently after completion reaction. present method provides powerful synthetic route to complex derivatives, demonstrating successful larger scale further molecular transformations B(9)-alkylated products.

Language: Английский

Directing Group Assisted Transition Metal Catalyzed Selective BH Functionalization of o-Carboranes DOI
Zuowei Xie, Jie Zhang

Synthesis, Journal Year: 2024, Volume and Issue: unknown

Published: June 11, 2024

Abstract Carboranes are a type of molecular clusters consisting carbon, hydrogen, and boron atoms. They possess unique characteristics, such as three-dimensional aromaticity, icosahedral geometry, robustness. Functionalized carboranes have been utilized in various fields, including medicine, materials, organometallic/coordination chemistry. In this context, selective functionalization o-carboranes has received tremendous attention, specifically the regio- enantioselective modification ten chemically similar BH vertices within carborane cage. recent years, significant progress made catalytic vertex-specific functionalization, well achieving cage BH. This review provides an overview advancements research field. 1 Introduction 2 Carboxy-Assisted Functionalization 2.1 Formation B–C Bonds 2.2 B–N 2.3 B–O 2.4 B–X 2.5 Consecutive B–Y (Y = N, O) 3 N-Based Directing-Group-Assisted B–H 3.1 Acylamino Directing Group 3.2 Amide 3.3 Pyridyl 3.4 Imine 4 Phosphinyl-Assisted Cage 5 Bidentate-Directing-Group-Assisted 6 Other 7 Conclusions

Language: Английский

Citations

3
Palladium catalyzed selective arylation of B(4)-H of o-carboranes with potassium aryltrifluoroborate DOI

Chao-Chao Teng,

Yan Guo, Ke Cao

et al.

Journal of Organometallic Chemistry, Journal Year: 2024, Volume and Issue: 1008, P. 123051 - 123051

Published: Feb. 26, 2024

Language: Английский

Citations

0
Photoredox-Catalyzed Difunctionalization of Alkenes with Sulfilimines DOI

Tingwei Yu,

Zhe Jin,

Yan Ji

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(37), P. 7944 - 7948

Published: Sept. 10, 2024

Herein, we disclose a facile photoinduced difunctionalization of alkenes, enabling the synthesis valuable β-amino alcohols, ethers, and 1,2-diamines with diverse nucleophiles. The protocol relies on use readily accessible dibenzothiophene-based sulfilimines as novel

Language: Английский

Citations

0
Rhodium(III)-Catalyzed B(4)-Azo Coupling of o-Carboranes with Aryl Diazonium Tetrafluoroborates DOI
Kyungsup Lee, S.‐K. YOON, Hee Chan Noh

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 25, 2024

Rh(III)-catalyzed B(4)-azo coupling reactions of

Language: Английский

Citations

0
Iridium(III)-catalyzed remote B(9)−H alkylation of o-carboranes with nitrile template DOI Creative Commons
Phil Ho Lee, Kyungsup Lee, Ji‐Won Kim

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: July 24, 2024

Abstract Although the directing group assisted ortho-B − H activation reactions of o-carboranes have been well established during past decade, meta-B are unexplored so far. Herein, iridium(III)-catalyzed remote B(9) alkylation with nitrile template demonstrated for first time. It was revealed that fine tuning structures is essential high reaction efficiency and regioselectivity. This process exhibits a broad substrate scope good functional tolerance under simple conditions. The template, readily accessible from o-carborane acids, can be removed conveniently after completion reaction. present method provides powerful synthetic route to complex derivatives, demonstrating successful larger scale further molecular transformations B(9)-alkylated products.

Language: Английский

Citations

0