Visible-Light-Induced Divergent C–H Esterification/Alkylation of Quinoxalin-2(1H)-ones with Aldehydes under Mild Conditions

Organic Letters, Journal Year: 2025, Volume and Issue: 27(10), P. 2526 - 2531

Published: March 5, 2025

Herein, we introduce an efficient and straightforward strategy for the selective C-H esterification alkylation of quinoxalin-2(1H)-ones with aldehydes. A key feature our study is ability to perform both using different types The reaction system highly compatible a range aldehydes, yielding C3-esterified C3-alkylated products in moderate-to-good yields. applicability this approach further enhanced by its scalability through continuous-flow synthesis, late-stage modification significant molecules, product derivatization. Our mechanistic investigations reveal radical relay mechanism, triggered hydrogen atom transfer process.

Language: Английский

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A concise synthesis of Se/Fe materials for catalytic oxidation reactions of anthracene and polyene

Chinese Chemical Letters, Journal Year: 2024, Volume and Issue: unknown, P. 110036 - 110036

Published: May 1, 2024

Language: Английский

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Se/ZrO₂-Catalyzed Oxidation of Phenol

Chinese Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 44(4), P. 1343 - 1343

Published: Jan. 1, 2024

Language: Английский

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Element transfer reaction theory: Scientific connotation and its applications in chemical industry

Chinese Chemical Letters, Journal Year: 2025, Volume and Issue: unknown, P. 110924 - 110924

Published: Feb. 1, 2025

Language: Английский

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Polymer-Supported Selenium Affording Opportunities in Catalyst Design

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 20, 2025

Polymer-supported selenium has been reported as a heterogeneous catalyst that is easily separated from the reaction system, thereby making recovery and reuse of more convenient. However, utilization polymer-supported in preparation catalysts not restricted to aforementioned technical advantages. Recent studies have shown small-molecule organoselenium significant performance differences, leading distinct mechanisms, which offer opportunities for development new organic reactions.

Language: Английский

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Activation of Molecular Oxygen and Selective Oxidation with Metal Complexes

Accounts of Chemical Research, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 21, 2025

ConspectusSelective oxidation with molecular oxygen is one of the most appealing approaches to functionalization organic molecules and, yet at same time, challenging reactions facing synthesis due poor selectivity control. Molecular a green and inexpensive oxidant, producing water as only byproduct in oxidation. Not surprisingly, it has been used manufacturing many commodity chemicals industry. It also nature's choice oxidant drives variety critical life various other biologic processes. While past decades have witnessed great progress understanding, both structurally mechanistically, how nature exploits metalloenzymes, i.e., monooxygenases dioxygenases, tackle some reactions, e.g., methane methanol, there are small number well-defined, man-made metal complexes that reported enable selective compounds more relevant fine chemical pharmaceutical synthesis.In 10 years or so, our laboratories developed several transition shown they capable catalyzing under 1 atm O2. Thus, we an Fe(II)-bisimidazolidinyl-pyridine complex catalyzes oxygenation C–H bonds ethers concomitant release hydrogen gas instead water, when iron center replaced Fe(III), oxidative cleavage C═C olefins becomes feasible. To address low activity oxidizing less active olefins, Mn(II)-bipyridine complex, which aliphatic C–C diols, carboxyl units carboxylic acids visible light irradiation. Light necessary cleave off-cycle, inactive manganese dimer into catalytically Mn═O oxo species. Furthermore, found binuclear salicylate-bridged Cu(II) enables tetrahydroisoquinolines well bond cleavage, catalytic vitamin B1 analogue brought in, lactams takes place via carbene catalysis. Still further, readily accessible Rh(II)-terpyridine alcohols, being water-soluble, catalyst can be easily separated reused multiple times. In addition, recently unearthed simple protocol allows waste polystyrene depolymerized isolable, valuable chemicals. A cheap Brønsted acid acts catalyst, activating singlet state through complexation polymer irradiation, thereby depolymerizing polymer.

Language: Английский

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Selective Oxidation of Tertiary Alcohols to Ketones via Synergistic Catalysis of (NH₄)₂Ce(NO₃)₆ and Trifluoroacetic Acid With Oxygen

cMat., Journal Year: 2025, Volume and Issue: 2(1)

Published: March 1, 2025

ABSTRACT Tertiary alcohols are generally considered difficult to oxidize. However, in this work, it was found that catalyzed by (NH 4 ) 2 Ce(NO 3 6 (CAN) and the presence of catalytic trifluoroacetic acid (TFA), selective oxidative C‐C bond cleavage tertiary could be achieved using O flow produce carbonyl compounds. The benefits method include use simple inexpensive catalysts, as well environmentally friendly nature process. This research significantly broadens scope alcohol oxidation chemistry. Since reactions involving have potential applications key unit reaction certain industrial processes, finding holds significant promise for organic chemical engineering.

Language: Английский

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An unexpected approach to enhance specific surface area and mesopore amount of polyaniline by Zn doping

Rare Metals, Journal Year: 2024, Volume and Issue: 43(9), P. 4585 - 4594

Published: May 25, 2024

Language: Английский

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Se/ZrO₂-Catalyzed Oxidative Polymerization of Aniline

Chinese Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 44(11), P. 3392 - 3392

Published: Jan. 1, 2024

Language: Английский

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Selenium and Alzheimer's disease

Chinese Chemical Letters, Journal Year: 2024, Volume and Issue: unknown, P. 110727 - 110727

Published: Dec. 1, 2024

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