Thioxanthone-TfOH complex (9-HTXTF) photoredox enabled reduction of sulfoxides

Tetrahedron Letters, Journal Year: 2024, Volume and Issue: 139, P. 155007 - 155007

Published: March 15, 2024

Language: Английский

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Successive Hydrolysis and Transfer Hydrogenation of 2-Chloroquinolines to 3,4-Dihydroquinolones

New Journal of Chemistry, Journal Year: 2024, Volume and Issue: 48(41), P. 17700 - 17705

Published: Jan. 1, 2024

A practical and efficient platform for the synthesis of 3,4-dihydroquinolones through successive hydrolysis transfer hydrogenation was presented. wide range 2-chloroquinolines were compatible with this catalytic system in excellent yields.

Language: Английский

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TBAB-catalyzed 1,6-conjugate diazotization of para-quinone methides: A very effective access to polysubstituted α-diazocarbonyl compounds

Journal of Saudi Chemical Society, Journal Year: 2024, Volume and Issue: 28(3), P. 101846 - 101846

Published: March 20, 2024

A highly efficient diazotization of diazoacetates with para-quinone methides has been established via a tetrabutyl ammonium bromide (TBAB)-catalyzed 1,6-conjugated addition pathway. This methodology affords convenient, safe, and rapid way to generating diverse polysubstituted α-diazocarbonyl compounds, displaying good functional group tolerance, high atom economy, easy accessibility.

Language: Английский

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Organophotocatalytic or Electrophotocatalytic Reduction and Functionalization Reactions with a Thioxanthone-TfOH Complex Catalyst

Synlett, Journal Year: 2024, Volume and Issue: unknown

Published: April 23, 2024

Abstract Thioxanthone has long been a prominent catalyst in the field of photocatalysis, owing to its high triplet energy and lifetime that render it suitable for transfer reactions. However, low oxidation potential short singlet have posed challenges when employing electron-transfer This account summarizes our efforts developing potent long-lived thioxanthone-TfOH complex (9-HTXTF) catalyst, application energy-demanding redox transformations such as organophotocatalytic or electrophotocatalytic reduction functionalization 1 Introduction 2 Discovery Properties Catalyst 9-HTXTF 3 Organophotocatalysis 4 Electrophotocatalysis 5 Conclusion

Language: Английский

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Mild Photochemical Reduction of Alkenes and Heterocycles via Thiol-Mediated Formate Activation

Organic Letters, Journal Year: 2024, Volume and Issue: 26(26), P. 5534 - 5538

Published: June 25, 2024

The reduction of alkenes to their respective alkanes is one the most important transformations in organic chemistry, given abundance natural and commercial olefins. Metal-catalyzed hydrogenation common way reduce alkenes; however, use H2 gas combination with precious metals required for these conditions can be impractical, dangerous, expensive. More complex substrates often require extremely high pressures H2, further emphasizing safety concerns associated reactions. Here we report a safe, cheap, practical photochemical alkene using readily available organophotocatalyst, catalytic thiol, formate. These variety di-, tri-, tetra-substituted good yield as well dearomatize pharmaceutically relevant heterocycles generate sp3-rich isosteres benzofurans indoles. formal-hydrogenation tolerate broad range functionalities that would otherwise sensitive typical hydrogenations are likely industry applications.

Language: Английский

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Visible-light-induced thiol-mediated transfer hydrogenation/deuteration of activated alkenes, imines and azo compounds

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

We have developed photochemical selective transfer hydrogenation/deuteration using H 2 O/D O as the H/D-source under metal-free conditions.

Language: Английский

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Generation of alkene radical cation for thioxanthone-TfOH complex-catalyzed intramolecular cyclization using a photoredox catalysis strategy

Journal of Catalysis, Journal Year: 2024, Volume and Issue: unknown, P. 115817 - 115817

Published: Oct. 1, 2024

Language: Английский

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