The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 9, 2024
A Ru(II)-catalyzed migratory insertion of carbene into
Language: Английский
The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 9, 2024
A Ru(II)-catalyzed migratory insertion of carbene into
Language: Английский
Chemical Communications, Journal Year: 2024, Volume and Issue: 60(23), P. 3150 - 3153
Published: Jan. 1, 2024
A silver-catalyzed phosphonation of 2-aryloxazolines has been accomplished. This protocol provides highly regioselective access to
Language: Английский
Citations
4Organic Letters, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 28, 2025
A novel Ru-catalyzed radical-triggered trifunctionalization of hexenenitriles is presented, employing a strategy remote cyano group migration and meta-C(sp2)-H functionalization. Through migration, the alkenyl moiety undergoes difunctionalization to formation benzylic radical intermediate. This intermediate facilitates para-selective C-H bond addition relative C-Ru within Ru(III) complex, ultimately enabling trifunctionalization. methodology provides an efficient route diverse array nitrile-containing compounds with broad functional compatibility.
Language: Английский
Citations
0Chemistry - An Asian Journal, Journal Year: 2025, Volume and Issue: unknown
Published: April 21, 2025
Abstract Photoredox fluoroalkylation has emerged as a powerful method and have unlocked new possibilities in organic chemistry. In this work, the green‐light‐induced copper‐mediated difluoroalkylation of arylsulfonium salts with different XCF 2 COR reagents is described. The reaction proceeded smoothly at ambient temperature under mild conditions allowed formation variety difluoroalkylated arenes good yields. photocatalyst, visible‐light, Cu(I) salt played synergetic role reduction to respective radical intermediates. This metallophotoredox protocol was applicable late‐stage multifunctionalized bioactive molecules, offering opportunities discovery medicinal agents. transformation showed advantages mildness, simple operation, functional group tolerance, wide range substrates, excellent regioselectivity, which provided an interesting alternative other reactions terms structural diversity, selectivity, availability by application platforms.
Language: Английский
Citations
0Asian Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: May 26, 2025
Abstract The difluoromethylene (CF 2 ) group is a highly valuable structural unit that significantly contributes to the research and development of novel pharmaceuticals. This work presents an effective synthesis CF ‐containing compounds from β‐nitrostyrene, facilitated by nickel chloride tetrahydroxydiboron. approach simple, efficient, selective, thus providing strategy for utilization β‐nitrostyrene.
Language: Английский
Citations
0Chemical Science, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 9, 2024
The direct functionalization of C–H bonds has revolutionized the field synthetic organic chemistry by enabling efficient and atom-economical modification arenes avoiding prefunctionalization.
Language: Английский
Citations
1Communications Chemistry, Journal Year: 2024, Volume and Issue: 7(1)
Published: Dec. 18, 2024
Synthetic chemistry approaches for direct C–H bond alkylation offers a promising alternative to traditional functional-group-centered strategies which often involve multi-step procedures and may suffer from variety of challenges including scalability. Here, we introduce resonant mixing as an efficient method meta-C–H arenes using Ru-catalyst, avoiding the need bulk solvents, external temperature, or light. The described methodology is highly rapid, enabling multigram-scale synthesis meta-alkylation products within short reaction time achieving very high turnover frequency. operates via radical mechanism characterized by its mild conditions, substrate compatibility, exceptional meta-selectivity, all while significantly reducing times. authors acoustic Ru-catalyst mechanism,
Language: Английский
Citations
1Tetrahedron, Journal Year: 2024, Volume and Issue: 167, P. 134303 - 134303
Published: Oct. 10, 2024
Language: Английский
Citations
0Organic Letters, Journal Year: 2024, Volume and Issue: 26(42), P. 9073 - 9078
Published: Oct. 15, 2024
A photoinduced vitamin-B
Language: Английский
Citations
0The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 9, 2024
A Ru(II)-catalyzed migratory insertion of carbene into
Language: Английский
Citations
0