Cited by Ru-Catalyzed <i>Ortho</i> C–H Alkylation of 4-Aryl-pyrrolo[2,3-<i>d</i>]pyrimidines with Diazo Compounds: An Access to Fluorescent Fused Heteroarenes

Silver(i)-catalyzed highly para-selective phosphonation of 2-aryloxazolines DOI

Pengcheng Cui, Guan‐Wu Wang

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(23), P. 3150 - 3153

Published: Jan. 1, 2024

A silver-catalyzed phosphonation of 2-aryloxazolines has been accomplished. This protocol provides highly regioselective access to

Language: Английский

Citations

Ruthenium-Catalyzed Remote Trifunctionalization of Non-Activated Alkenes via Cyano Migration and meta-C(sp²)–H Functionalization DOI

Junlei Zhang, Xixi Zhao,

You-Zhi Liao

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 28, 2025

A novel Ru-catalyzed radical-triggered trifunctionalization of hexenenitriles is presented, employing a strategy remote cyano group migration and meta-C(sp2)-H functionalization. Through migration, the alkenyl moiety undergoes difunctionalization to formation benzylic radical intermediate. This intermediate facilitates para-selective C-H bond addition relative C-Ru within Ru(III) complex, ultimately enabling trifunctionalization. methodology provides an efficient route diverse array nitrile-containing compounds with broad functional compatibility.

Language: Английский

Citations

Photoinduced Copper‐Mediated Difluoroalkylation of Arylsulfonium Salts with XCF₂COR DOI

Xia Fang,

Yan‐Hao Wang,

Xiaotao Ding

et al.

Chemistry - An Asian Journal, Journal Year: 2025, Volume and Issue: unknown

Published: April 21, 2025

Abstract Photoredox fluoroalkylation has emerged as a powerful method and have unlocked new possibilities in organic chemistry. In this work, the green‐light‐induced copper‐mediated difluoroalkylation of arylsulfonium salts with different XCF 2 COR reagents is described. The reaction proceeded smoothly at ambient temperature under mild conditions allowed formation variety difluoroalkylated arenes good yields. photocatalyst, visible‐light, Cu(I) salt played synergetic role reduction to respective radical intermediates. This metallophotoredox protocol was applicable late‐stage multifunctionalized bioactive molecules, offering opportunities discovery medicinal agents. transformation showed advantages mildness, simple operation, functional group tolerance, wide range substrates, excellent regioselectivity, which provided an interesting alternative other reactions terms structural diversity, selectivity, availability by application platforms.

Language: Английский

Citations

Nickel(II) Chloride Catalyzed and Tetrahydroxydiboron Promoted Denitrative Difluoroalkylation of β‐Nitrovinylarene DOI

Siyi Zhong,

Yingfan Yang,

Xiangwei Ren

et al.

Asian Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: May 26, 2025

Abstract The difluoromethylene (CF 2 ) group is a highly valuable structural unit that significantly contributes to the research and development of novel pharmaceuticals. This work presents an effective synthesis CF ‐containing compounds from β‐nitrostyrene, facilitated by nickel chloride tetrahydroxydiboron. approach simple, efficient, selective, thus providing strategy for utilization β‐nitrostyrene.

Language: Английский

Citations

Photocatalytic Regioselective C–H Bond Functionalizations in Arenes DOI

Jun Hu, Suman Pradhan, Satyadeep Waiba

et al.

Chemical Science, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 9, 2024

The direct functionalization of C–H bonds has revolutionized the field synthetic organic chemistry by enabling efficient and atom-economical modification arenes avoiding prefunctionalization.

Language: Английский

Citations

Rapid and scalable ruthenium catalyzed meta-C–H alkylation enabled by resonant acoustic mixing DOI

Arnab Dey, Rajesh Kancherla, Kuntal Pal

et al.

Communications Chemistry, Journal Year: 2024, Volume and Issue: 7(1)

Published: Dec. 18, 2024

Synthetic chemistry approaches for direct C–H bond alkylation offers a promising alternative to traditional functional-group-centered strategies which often involve multi-step procedures and may suffer from variety of challenges including scalability. Here, we introduce resonant mixing as an efficient method meta-C–H arenes using Ru-catalyst, avoiding the need bulk solvents, external temperature, or light. The described methodology is highly rapid, enabling multigram-scale synthesis meta-alkylation products within short reaction time achieving very high turnover frequency. operates via radical mechanism characterized by its mild conditions, substrate compatibility, exceptional meta-selectivity, all while significantly reducing times. authors acoustic Ru-catalyst mechanism,

Language: Английский

Citations

Visible-light-promoted one-pot synthesis of β-keto sulfones from aryldiazo tetrafluoroborate salts via aerobic multicomponent reaction DOI

Truong Giang Luu, Hee‐Kwon Kim

Tetrahedron, Journal Year: 2024, Volume and Issue: 167, P. 134303 - 134303

Published: Oct. 10, 2024

Language: Английский

Citations

Photoinduced Vitamin-B₁₂-Catalyzed meta-C–H Bromination/Chlorination of Phenol Derivatives Assisted by a U-Shaped Nitrile Template DOI

Weiya Zhang,

Xianghui Zhu,

Huixin Tong

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(42), P. 9073 - 9078

Published: Oct. 15, 2024

A photoinduced vitamin-B

Language: Английский

Citations

Ru-Catalyzed Ortho C–H Alkylation of 4-Aryl-pyrrolo[2,3-d]pyrimidines with Diazo Compounds: An Access to Fluorescent Fused Heteroarenes DOI

Jiangrong Wang, Chunfeng Li,

Chunwei Shen

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 9, 2024

A Ru(II)-catalyzed migratory insertion of carbene into

Language: Английский

Citations