A review of recent advances in electrochemical and photoelectrochemical late-stage functionalization classified by anodic oxidation, cathodic reduction, and paired electrolysis
Beilstein Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
20, P. 2500 - 2566
Published: Oct. 9, 2024
With
the
resurgence
of
electrosynthesis
in
organic
chemistry,
there
is
a
significant
increase
number
routes
available
for
late-stage
functionalization
(LSF)
drugs.
Electrosynthetic
methods,
which
obviate
need
hazardous
chemical
oxidants
or
reductants,
offer
unprecedented
control
reactions
through
continuous
variation
applied
potential
and
possibility
combination
with
photochemical
processes.
This
capability
substantial
advantage
performing
electrochemical
photoelectrochemical
LSF.
Ultimately,
these
protocols
are
poised
to
become
vital
component
medicinal
chemist's
toolkit.
In
this
review,
we
discuss
that
have
been
demonstrated
be
applicable
LSF
pharmaceutical
drugs,
their
derivatives,
natural
substrates.
We
present
analyze
representative
examples
illustrate
electrochemistry
photoelectrochemistry
valuable
molecular
scaffolds.
Language: Английский
Nickel-Catalyzed Stereoconvergent C(sp2)–F Alkenylation of Monofluoroalkenes
Xiaowei Li,
No information about this author
Wenlong Shan,
No information about this author
Nan Zhou
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et al.
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(40), P. 8521 - 8526
Published: Sept. 27, 2024
The
stereoconvergent
synthesis
of
a
single
stereoisomer
from
Language: Английский
Advancements in the Selective Transformation of Olefins to New C-C Bonds through Cooperative Catalysis Involving Electrochemistry and Transition Metals
Chunxiao Nong,
No information about this author
Yi Jin
No information about this author
Tetrahedron,
Journal Year:
2024,
Volume and Issue:
unknown, P. 134330 - 134330
Published: Oct. 1, 2024
Language: Английский
Electrochemical Synthesis of Phosphorus-Containing Glycines and Peptides via Triarylamine-Catalyzed Dehydrogenative C(sp3)-P Coupling
Green Chemistry,
Journal Year:
2024,
Volume and Issue:
27(3), P. 566 - 572
Published: Dec. 6, 2024
An
atom-economical
and
sustainable
electrochemically
driven
triarylamine-catalyzed
dehydrogenative
phosphorylation
coupling
was
reported.
Language: Английский