Molecular Diversity, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 1, 2024
Language: Английский
The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(11), P. 8286 - 8290
Published: May 14, 2024
Cyclizations of NH-S-(2-hydroxyaryl)sulfoximines with 1,1′-carbonyldiimidazol (CDI) give unprecedented benzo[e][1,4,3]oxathiazin-3-one 1-oxides in good yields. The standard synthetic protocol involves the use DCE at an increased temperature for 16 h. Under mechanochemical conditions, a representative product was obtained without solvent ambient only 60 min. X-ray single-crystal structure analysis confirmed molecular scaffold representing three-dimensional heterocycle.
Language: Английский
Citations
1
Chemical Communications, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Cascade C–C/C–N bond formation of carbonyl ylides with azaoxyallyl cations generated in situ using Rh-catalysis has been accomplished the presence a base at room temperature.
Language: Английский
Citations
1
Asian Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 13, 2024
Abstract The N−H insertion reaction is a versatile method for creating C−N bonds under mild conditions, providing in particular an efficient access to both natural and non‐natural α‐amino acid derivatives. In this field, the direct on α‐diazo‐β‐hydroxyesters has not yet been investigated constitutes significant challenge, due competitive migration processes. We report herein first insertions O ‐protected α‐diazo‐β‐aryl‐β‐hydroxyesters, enabling synthesize wide range of α‐amino‐β‐hydroxyesters by tuning nature amine aryl substituent. Overall, 28 products have isolated, with moderate good yields most cases, diastereoisomeric ratios up 8.0 : 1 favor syn diastereoisomer.
Language: Английский
Citations
0
Molecular Diversity, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 1, 2024
Language: Английский
Citations
0