Dehydrogenative Coupling Reactions with Guanidino‐Functionalized Aromatics DOI Creative Commons

Petra Walter,

Maximilian Schulz,

Olaf Hübner

et al.

Chemistry - A European Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 7, 2024

Dehydrogenative coupling (DC) reactions are of importance for the construction new carbon-element bonds in synthetic organic chemistry. In this work, we report on synthesis and characterization several redox-active guanidino-functionalized aromatic molecules (GFAs) use DC (C-C C-O) reactions. a systematic approach, first characterize reagents all relevant redox protonation states, compare their performance competitive test proton-coupled electron transfer (PCET) Then, four different with mechanisms is evaluated.

Language: Английский

Electrosynthesis of 1,4-diene derivatives bearing cyclopentene skeleton DOI Creative Commons

Yaqi Qiao,

Xiaoqing Fan,

Chengcheng Yuan

et al.

iScience, Journal Year: 2025, Volume and Issue: 28(3), P. 111976 - 111976

Published: Feb. 10, 2025

1,n-Dual Π systems including 1,4-diene derivatives have been widely used as the elegant radical receptors to promote cascade additions give highly functionalized polycyclic scaffolds. However, tedious and complicated preparation of former deters broad utilization compromises practical value. Herein, a straightforward was developed from easily accessible alkynes γ,δ-unsaturated carboxylic acids via electrochemical oxidation cyclization Hofmann elimination. This transformation features with good excellent yields, functional group compatibility, selectivity without any Zaitsev elimination product detected.

Language: Английский

Citations

0
De novo synthesis of 6-6-5 fused-systems through electrochemical decarboxylation and radical domino additions DOI

Chengcheng Yuan,

Guanru Liu,

Wenjing Guan

et al.

Green Chemistry, Journal Year: 2024, Volume and Issue: 26(19), P. 10308 - 10313

Published: Jan. 1, 2024

An oxidant and quaternary ammonium salt-free electrosynthesis of 6-6-5 fused systems was developed with excellent atom step economy.

Language: Английский

Citations

1
Dehydrogenative Coupling Reactions with Guanidino‐Functionalized Aromatics DOI Creative Commons

Petra Walter,

Maximilian Schulz,

Olaf Hübner

et al.

Chemistry - A European Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 7, 2024

Dehydrogenative coupling (DC) reactions are of importance for the construction new carbon-element bonds in synthetic organic chemistry. In this work, we report on synthesis and characterization several redox-active guanidino-functionalized aromatic molecules (GFAs) use DC (C-C C-O) reactions. a systematic approach, first characterize reagents all relevant redox protonation states, compare their performance competitive test proton-coupled electron transfer (PCET) Then, four different with mechanisms is evaluated.

Language: Английский

Citations

0