Silver-Catalyzed Doyle–Kirmse Reaction of Allyl Sulfides with Vinyl Triftosylhydrazones
Organic Letters,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 7, 2025
Here,
we
report
a
general
and
practical
Doyle-Kirmse
reaction
of
allyl/propargyl
sulfides
with
donor-only
vinyl
carbenes
generated
in
situ
from
triftosylhydrazones
the
presence
silver
catalyst.
This
protocol
features
mild
conditions,
exhibits
broad
substrate
scope
exceptional
functional
group
tolerance,
provides
corresponding
1,5-dienyl
1,4-enallenyl
high
yields.
Moreover,
gram-scale
synthesis,
late-stage
modifications
complex
molecules,
post-synthetic
transformations
were
performed
to
demonstrate
applicability
this
protocol.
Language: Английский
Rhodium(II)-Catalyzed Alkynyl Carbene Insertion into N–H Bonds
Akashdeep Sharma,
No information about this author
Himani Vaid,
No information about this author
Riya Kotwal
No information about this author
et al.
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(23), P. 4887 - 4892
Published: June 6, 2024
The
first
insertion
of
an
alkynyl
carbene
into
N–H
bonds
under
Rh-catalysis
is
developed.
Alkynyl
hydrazone
carboxylates
are
used
as
donor–acceptor
precursors
and
exquisitely
inserted
the
various
amines,
amides,
1,2-diamines.
A
wide
variety
3-alkynyl
3,4-dihydroquinoxalin-2(1H)-ones
densely
functionalized
α-alkynyl
α-amino
esters
obtained
in
good
to
excellent
yields.
Further,
chemoselective
reactions,
mechanistic
studies,
synthetic
transformations
for
obtaining
valuable
heterocycles
demonstrated.
Language: Английский
On-water synthesis of 3,6-dihydro-2H-thiopyrans: Doyle-Kirmse reaction induced by blue-LED and ring-closing metathesis
New Journal of Chemistry,
Journal Year:
2024,
Volume and Issue:
48(32), P. 14305 - 14310
Published: Jan. 1, 2024
Water-mediated
synthesis
of
3,6-dihydro-2
H
-thiopyrans
from
diallyl
sulfides
and
diazo
compounds
via
Doyle–Kirmse
reaction
induced
by
blue-LEDs
ring-closing
metathesis.
Language: Английский