Cobalt-Catalyzed (3 + 2) Cycloaddition of Cyclopropene-Tethered Alkynes: Versatile Access to Bicyclic Cyclopentadienyl Systems and Their CpM Complexes DOI Creative Commons
Carlos Lázaro‐Milla, Eduardo da Concepción, Israel Fernández

et al.

ACS Catalysis, Journal Year: 2024, Volume and Issue: 14(15), P. 11574 - 11583

Published: July 20, 2024

Low-valent cobalt complexes can promote intramolecular (3 + 2) cycloadditions of alkyne-tethered cyclopropenes to provide bicyclic systems containing highly substituted cyclopentadienyl moieties with electronically diverse functional groups. The adducts be easily transformed into new types CpRh(III) and CpIr(III) complexes, which show catalytic activity in several relevant transformations. Preliminary computational (DFT) experimental studies information on the mechanistic peculiarities cobalt-catalyzed process allow us rationalize its advantages over homologous rhodium-promoted reaction.

Language: Английский

Temperature‐Dependent Regiodivergent Synthesis of Functionalized Maleimides and Itaconimides via in‐situ Generated Pyridinium Ylide DOI Open Access
Suman Saha,

Anupriya Bera,

Akanksha Kumari

et al.

European Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 11, 2025

Abstract We report a temperature‐dependent regiodivergent synthetic strategy for the construction of functionalized maleimides and itaconimides using in‐situ generated pyridinium ylides. This approach enables efficient access to both regioisomeric products under mild straightforward reaction conditions. A variety salts with different aromatic alkyl groups were successfully used N ‐aryl ‐alkyl succinimides demonstrating broad substrate compatibility. The practicality scalability this methodology confirmed through scale‐up experiments, which maintained high yields reproducibility.

Language: Английский

Citations

1
Synthesis of Multisubstituted Cyclopentadiene Derivatives from 3,3-Disubstituted Cyclopropenes and Internal Alkynes Catalyzed by Low-Valent Niobium Complexes DOI
Takuya Akiyama, Tetsuro Kusamoto, Kazushi Mashima

et al.

Journal of the American Chemical Society, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 22, 2024

A low-valent niobium species generated from NbCl

Language: Английский

Citations

4
Cobalt-Catalyzed (3 + 2) Cycloaddition of Cyclopropene-Tethered Alkynes: Versatile Access to Bicyclic Cyclopentadienyl Systems and Their CpM Complexes DOI Creative Commons
Carlos Lázaro‐Milla, Eduardo da Concepción, Israel Fernández

et al.

ACS Catalysis, Journal Year: 2024, Volume and Issue: 14(15), P. 11574 - 11583

Published: July 20, 2024

Low-valent cobalt complexes can promote intramolecular (3 + 2) cycloadditions of alkyne-tethered cyclopropenes to provide bicyclic systems containing highly substituted cyclopentadienyl moieties with electronically diverse functional groups. The adducts be easily transformed into new types CpRh(III) and CpIr(III) complexes, which show catalytic activity in several relevant transformations. Preliminary computational (DFT) experimental studies information on the mechanistic peculiarities cobalt-catalyzed process allow us rationalize its advantages over homologous rhodium-promoted reaction.

Language: Английский

Citations

2