Photoredox/Sulfide Dual Catalysis for Modular Synthesis of Multi‐Substituted Furan Rings via Catalytic Indirect Reductive Quenching DOI Open Access
Kakeru Matsukuma, Masanori Tayu,

Takumi Ogino

et al.

Chemistry - An Asian Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 7, 2025

The catalytic indirect reductive quenching method is facilitated by a combination of Ir(III) photoredox and sulfide dual-catalysis system. This study demonstrated for synthesizing multi-substituted furans using photoredox/sulfide enables the synthesis various furan derivatives, including spirofurans phthalans. utility this system was through gram-scale pharmaceutical molecule talopram. Mechanistic studies density functional theory calculations suggested formation sulfonium species via radical cations, followed intramolecular cyclization to produce desired derivatives.

Language: Английский

Direct C(sp3)-H functionalization with aryl and alkyl radicals as intermolecular hydrogen atom transfer (HAT) agents DOI
Jia‐Lin Tu, Binbin Huang

Chemical Communications, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Recent years have witnessed the emergence of direct intermolecular C(sp

Language: Английский

Citations

9
Photoredox/Sulfide Dual Catalysis for Modular Synthesis of Multi‐Substituted Furan Rings via Catalytic Indirect Reductive Quenching DOI Open Access
Kakeru Matsukuma, Masanori Tayu,

Takumi Ogino

et al.

Chemistry - An Asian Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 7, 2025

The catalytic indirect reductive quenching method is facilitated by a combination of Ir(III) photoredox and sulfide dual-catalysis system. This study demonstrated for synthesizing multi-substituted furans using photoredox/sulfide enables the synthesis various furan derivatives, including spirofurans phthalans. utility this system was through gram-scale pharmaceutical molecule talopram. Mechanistic studies density functional theory calculations suggested formation sulfonium species via radical cations, followed intramolecular cyclization to produce desired derivatives.

Language: Английский

Citations

0