Chemistry - An Asian Journal, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 7, 2025
The catalytic indirect reductive quenching method is facilitated by a combination of Ir(III) photoredox and sulfide dual-catalysis system. This study demonstrated for synthesizing multi-substituted furans using photoredox/sulfide enables the synthesis various furan derivatives, including spirofurans phthalans. utility this system was through gram-scale pharmaceutical molecule talopram. Mechanistic studies density functional theory calculations suggested formation sulfonium species via radical cations, followed intramolecular cyclization to produce desired derivatives.
Language: Английский