Palladium-Catalyzed Dual-Tasked ortho-C–H Borylation of Aryl Iodides DOI
Shuai Yang, Fanyi Meng, Yanghui Zhang

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 5, 2024

The Pd-catalyzed ortho-C–H borylation of aryl iodides has been developed through maleimide-relayed C–H activation. In this reaction, the ipso-positions and bonds are alkylated borylated, respectively, providing a new strategy for borylation. reaction exhibits broad substrate scope represents modular synthetic method functionalized 3-aryl succinimides, which essential structural motifs in organic compounds with diverse biological activities. Furthermore, boronate group can be further manipulated, practical utility demonstrated. This work also introduces ipso, ortho-difunctionalization halides via

Language: Английский

Advances in Palladium-Catalyzed C(sp3)–H Functionalization: The Role of Traceless Directing Groups DOI
Masoud Sadeghi

ACS Catalysis, Journal Year: 2024, Volume and Issue: unknown, P. 15356 - 15373

Published: Oct. 3, 2024

Language: Английский

Citations

5
Palladium-catalyzed intermolecular formal [3+2] cyclization/C-H alkylation of polyfluoroarenes DOI
Zhongyao Jiang, Chenglin Liu,

Mingxia Wu

et al.

Chemical Communications, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

A sequential three-component intermolecular carbopalladation/Heck cyclization/intermolecular C–H bond functionalization for versatile alkylated polyfluoroarenes containing an indene skeleton is presented.

Language: Английский

Citations

0
Late-Stage Modification of Peptides with Maleimides through Palladium-Catalyzed β-C(sp3)–H Alkylation DOI

Fengjie Lu,

Yujie Geng,

Huihui Wang

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 4, 2024

Transition-metal-catalyzed C-H activation has proven to be a powerful tool for the late-stage modification of peptides. We herein report method site-selective alkylation peptides with maleimides through Pd-catalyzed β-C(sp

Language: Английский

Citations

1
Recent Advances for the Transformation of Maleimides via Annulation DOI
Mohammad Aslam, Muhammad Saeed Akhtar, Hee Nam Lim

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

This review highlights recent advances in maleimide-based annulation and cyclization strategies, offering insights into their synthetic versatility potential applications creating structurally diverse aromatics bioactive heterocycles.

Language: Английский

Citations

0
Palladium-Catalyzed Dual-Tasked ortho-C–H Borylation of Aryl Iodides DOI
Shuai Yang, Fanyi Meng, Yanghui Zhang

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 5, 2024

The Pd-catalyzed ortho-C–H borylation of aryl iodides has been developed through maleimide-relayed C–H activation. In this reaction, the ipso-positions and bonds are alkylated borylated, respectively, providing a new strategy for borylation. reaction exhibits broad substrate scope represents modular synthetic method functionalized 3-aryl succinimides, which essential structural motifs in organic compounds with diverse biological activities. Furthermore, boronate group can be further manipulated, practical utility demonstrated. This work also introduces ipso, ortho-difunctionalization halides via

Language: Английский

Citations

0