Electrochemical Selenized Reaction of N-Arylbicyclo[1.1.0]butane-1-carboxamides: Access to 3-(Arylselanyl)spiro[cyclobutane-1,3′-indolin]-2′-one Derivatives DOI

Jiyao Liu,

Yuliang Qian,

Hongrong Zhao

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(21), P. 15914 - 15923

Published: Oct. 23, 2024

A novel selenized reaction of N-arylbicyclo [1.1.0]butane-1-carboxamides with diselenide for the synthesis polycyclic indoline derivatives is developed under electrochemical conditions. The achieved by bicyclo[1.1.0]butane strain-release and intramolecular cyclization process. In addition, this approach features a wide range substrates, good group tolerance, shorter time, mild

Language: Английский

Palladium-catalyzed allylic amination of vinyl bicyclo[1.1.0]butanes: a strain release approach toward alkylidenecyclobutanes DOI Creative Commons
Huan Zhang, Wenjie Liang, Jun‐An Xiao

et al.

Green Synthesis and Catalysis, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024

Language: Английский

Citations

2
Reductive Olefin Bicyclo[1.1.0]butane Coupling Enabled by Iron Hydride Hydrogen Atom Transfer DOI
Guang Chen,

Dayu Tian,

Xiaocheng Wang

et al.

ACS Catalysis, Journal Year: 2024, Volume and Issue: unknown, P. 14928 - 14936

Published: Sept. 25, 2024

Language: Английский

Citations

1
Visible-Light-Mediated Strain-Release Radical Spirocyclizations: Access to Functionalized Spirocyclobutanes DOI
Durga Prasad Hari, Tushar Singha

Synlett, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 15, 2024

Abstract Spirocyclobutanes have gained significant attention in medicinal chemistry discovery programs due to their broad spectrum of biological activities and clinical applications. Utilizing ring strain small molecules drive organic transformations is one the most powerful tools chemical synthesis. Our research group has focused on developing new synthetic strategies enabled by construct complex selectively efficiently. This account summarizes our recent efforts toward synthesis a library functionalized spirocyclobutanes harnessing bicyclo[1.1.0]butanes. Three spicrocyclization cascades been developed incorporate diverse range radical precursors into spirocycobutanes. 1 Introduction 2 Synthesis Spirocyclobutyl Lactones -Lactams using Bifunctional Reagents 3 Dual Photoredox/Nickel Catalysis for Lactams 4 Oxindoles under Photoredox 5 DFT Studies 6 Conclusion

Language: Английский

Citations

0
Electrochemical Selenized Reaction of N-Arylbicyclo[1.1.0]butane-1-carboxamides: Access to 3-(Arylselanyl)spiro[cyclobutane-1,3′-indolin]-2′-one Derivatives DOI

Jiyao Liu,

Yuliang Qian,

Hongrong Zhao

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(21), P. 15914 - 15923

Published: Oct. 23, 2024

A novel selenized reaction of N-arylbicyclo [1.1.0]butane-1-carboxamides with diselenide for the synthesis polycyclic indoline derivatives is developed under electrochemical conditions. The achieved by bicyclo[1.1.0]butane strain-release and intramolecular cyclization process. In addition, this approach features a wide range substrates, good group tolerance, shorter time, mild

Language: Английский

Citations

0