Remote C(sp3)–H Carboxylation with CO2 via Visible-Light-Catalyzed 1,5-Hydrogen Atom Transfer DOI
Haoran Huang, Xiaoyu Lin,

Fanyuanhang Yang

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 13, 2024

The direct carboxylation of C(sp3)–H bonds with CO2 represents a challenging but highly attractive strategy in organic synthesis. In this study, we presented visible-light-catalyzed for carboxylating remote via aryl radical induced 1,5-hydrogen atom transfer. This transformation involves generating alkyl radicals transfer from radicals, forming carbanions as key intermediates, and subsequent nucleophilic attack CO2, thereby enabling access to variety tertiary quaternary carboxylic acids moderate good yields.

Language: Английский

Photoredox/NHC cooperative catalysis for alkylacylation of styrenes: An alternative method for the synthesis of γ-aminoketones DOI

Ke-Yang Yu,

Fu Cheng,

Dong-Sen Duan

et al.

Tetrahedron Letters, Journal Year: 2025, Volume and Issue: 156, P. 155450 - 155450

Published: Jan. 8, 2025

Language: Английский

Citations

1
Remote C(sp3)–H Carboxylation with CO2 via Visible-Light-Catalyzed 1,5-Hydrogen Atom Transfer DOI
Haoran Huang, Xiaoyu Lin,

Fanyuanhang Yang

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 13, 2024

The direct carboxylation of C(sp3)–H bonds with CO2 represents a challenging but highly attractive strategy in organic synthesis. In this study, we presented visible-light-catalyzed for carboxylating remote via aryl radical induced 1,5-hydrogen atom transfer. This transformation involves generating alkyl radicals transfer from radicals, forming carbanions as key intermediates, and subsequent nucleophilic attack CO2, thereby enabling access to variety tertiary quaternary carboxylic acids moderate good yields.

Language: Английский

Citations

2