The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 16, 2024

The first Ru(II)-catalyzed C–H activation/[4 + 2] annulation of aryl imidates with heteroaromatic iodonium ylides is reported. Our approach features the utilization a commercially available ruthenium catalyst, providing one-step construction phelligridin analogues from easily and nonpreactivated starting materials. developed methodology successfully employed for total synthesis A, significantly streamlining previous multistep synthesis. potential this further demonstrated through modular core structure C/D.

Language: Английский