Photoredox Radical Truce–Smiles Rearrangement of N-Sulfinyl Acrylamides with Bromodifluoroacetamides DOI
Lin Tian, Pu Chen, Xiaochen Ji

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 18, 2024

We herein report a photochemical Truce–Smiles rearrangement reaction of N-sulfinyl acrylamides with bromodifluoroacetamides resulting in the synthesis series aryl difluoroglutaramides moderate to good yields. The asymmetric using chiral sulfinamides produced quaternary carbon-centered glutaramide products modest enantioselectivity. This protocol effectively complements previous methods involving N-sulfonyl acrylamides.

Language: Английский

A Catalyst- and Thiol-Free Protocol for Arene C–H Thioetherification via Photoactive Electron Donor–Acceptor Complexes DOI
Ang Gao,

Hongqiong Liu,

Yanan Zhou

et al.

Green Chemistry, Journal Year: 2025, Volume and Issue: 27(8), P. 2286 - 2292

Published: Jan. 1, 2025

We present a catalyst- and thiol-free protocol for arene C–H thioetherification under visible light irradiation.

Language: Английский

Citations

0
Copper-Catalyzed Regioselective 1,4-Sulfonyl Indolylation of 1,3-Dienes with Sulfonyl Chloride and Indoles DOI
Pu Chen, Lin Tian, Xiaochen Ji

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 22, 2025

A copper-based catalytic system has been described to enable the efficient 1,4-sulfonylindolylation of 1,3-dienes with sulfonyl chloride and indoles. This protocol offers a practical method for synthesis allylsulfone-containing indole derivatives broad range compatible functionalities excellent chemo- regioselectivities. Mechanistic studies suggest that copper catalyst plays dual role initiating radicals prompting coupling in this conjugated diene-selective 1,4-difunctionalization strategy.

Language: Английский

Citations

0
Access to quaternary-carbon-containing β-alkyl amides via persulfate-promoted domino alkylation/smiles rearrangement of alkenes DOI Creative Commons
Xiaohu Yang, Xiaoqing Wan, Wenchao Yang

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(20), P. 16183 - 16186

Published: Jan. 1, 2025

An efficient radical alkylative annulation/arylation of N -(arylsulfonyl)acrylamide with 4-alkyl-1,4-dihydropyridines (DHP) was developed for synthesizing all-carbon quaternary-centered β-alkyl amides.

Language: Английский

Citations

0
Synthesis of succinyldiamides containing all-quaternary carbon center by photo-induced amidation/smiles rearrangement of alkenes DOI
Yuyu Dai, Wei Niu, Jiapeng Huang

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 23, 2024

A novel, mild, and environmentally friendly method was developed for the synthesis of quaternary-carbon-containing succinyldiamides. This found to be compatible with many substrates.

Language: Английский

Citations

1
Photoredox Radical Truce–Smiles Rearrangement of N-Sulfinyl Acrylamides with Bromodifluoroacetamides DOI
Lin Tian, Pu Chen, Xiaochen Ji

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 18, 2024

We herein report a photochemical Truce–Smiles rearrangement reaction of N-sulfinyl acrylamides with bromodifluoroacetamides resulting in the synthesis series aryl difluoroglutaramides moderate to good yields. The asymmetric using chiral sulfinamides produced quaternary carbon-centered glutaramide products modest enantioselectivity. This protocol effectively complements previous methods involving N-sulfonyl acrylamides.

Language: Английский

Citations

0