Recent advances in the Rh-catalyzed cascade arene C–H bond activation/annulation toward diverse heterocyclic compounds DOI
Chang Wang, Fan Chen, Peng‐Cheng Qian

et al.

Organic & Biomolecular Chemistry, Journal Year: 2021, Volume and Issue: 19(8), P. 1705 - 1721

Published: Jan. 1, 2021

A review highlighting the advances in Cp*Rh(iii) catalysed cascade arene C–H activation/annulation including application, scope, limitations and mechanism of these transformations.

Language: Английский

Rhodium(III)-Catalyzed Annulative Coupling of Sulfoxonium Ylides and Allenoates: An Arene C–H Activation/Cyclopropanation Cascade DOI
Jiang Lou, Quannan Wang, Yong‐Gui Zhou

et al.

Organic Letters, Journal Year: 2019, Volume and Issue: 21(22), P. 9217 - 9222

Published: Nov. 5, 2019

Rhodium(III)-catalyzed annulative coupling of sulfoxonium ylides with allenoates was achieved, forming highly functionalized cyclopropanes a quaternary carbon center by means the ylide functionality as traceless bifunctional directing group and C4 synthon via an arene C–H activation cyclopropanation cascade. The protocol features simultaneous formation three new C–C bonds in one pot excellent diastereoselectivity. resultant products could be further transformed to diverse synthetically useful compounds.

Language: Английский

Citations

59
Thioether-Directed C4-Selective C–H Acylmethylation of Indoles Using α-Carbonyl Sulfoxonium Ylides DOI

Chandrababu Naidu Kona,

Yuji Nishii, Masahiro Miura

et al.

Organic Letters, Journal Year: 2020, Volume and Issue: 22(12), P. 4806 - 4811

Published: June 1, 2020

Site-selective direct functionalization of an indole benzenoid core has been a great challenge due to its inherently poor reactivity. We herein demonstrate iridium-catalyzed C4-selective acylmethylation indoles using α-carbonyl sulfoxonium ylides as carbene precursors. This method exhibits high efficiency and broad functional group compatibility. The directing was easily removed or converted other functionalities after the catalysis. potential synthetic utility coupling products highlighted by constructing medium-sized polycyclic indoles.

Language: Английский

Citations

59
Rhodium(III)-catalyzed intermolecular cyclization of anilines with sulfoxonium ylides toward indoles DOI

Zhihao Shen,

Chao Pi, Xiuling Cui

et al.

Chinese Chemical Letters, Journal Year: 2019, Volume and Issue: 30(7), P. 1374 - 1378

Published: Feb. 3, 2019

Language: Английский

Citations

56
Rhodium(III)-Catalyzed Regioselective C3–H Acylmethylation of [2,2′-Bipyridine]-6-carboxamides with Sulfoxonium Ylides DOI
Jia Yu,

Si Wen,

Dan Ba

et al.

Organic Letters, Journal Year: 2019, Volume and Issue: 21(16), P. 6366 - 6369

Published: July 30, 2019

A rhodium(III)-catalyzed C–H acylmethylation of tridentate [2,2′-bipyridine]-6-carboxamides was developed. variety could be monoalkylated exclusively at the C3 position with sulfoxonium ylides as carbene precursors, giving 3-alkylated products in high yields. This protocol proceeds through a rollover cyclometalation pathway, has broad range scope substrates, and exhibits excellent functional group tolerance.

Language: Английский

Citations

56
Recent advances in the Rh-catalyzed cascade arene C–H bond activation/annulation toward diverse heterocyclic compounds DOI
Chang Wang, Fan Chen, Peng‐Cheng Qian

et al.

Organic & Biomolecular Chemistry, Journal Year: 2021, Volume and Issue: 19(8), P. 1705 - 1721

Published: Jan. 1, 2021

A review highlighting the advances in Cp*Rh(iii) catalysed cascade arene C–H activation/annulation including application, scope, limitations and mechanism of these transformations.

Language: Английский

Citations

49