Organic & Biomolecular Chemistry,
Journal Year:
2023,
Volume and Issue:
21(8), P. 1591 - 1628
Published: Jan. 1, 2023
Photoredox
catalysis
has
demonstrated
rapid
evolution
in
the
field
of
synthetic
organic
chemistry.
On
other
hand,
splendour
cascade
reactions
providing
complex
molecular
architectures
renders
them
a
cutting-edge
research
area.
Therefore,
merging
photocatalysis
with
synthesis
brings
out
paradigm
immense
potential.
The
development
photocascade
for
target
molecule
particular
skeleton
and
stereochemical
framework
presents
certain
challenges
but
provides
robust
environmentally
benign
alternative.
This
comprehensive
review
assembles
all
accomplishments
highlights
visible-light-induced
literature
coverage
up
to
October
2022.
Organic & Biomolecular Chemistry,
Journal Year:
2019,
Volume and Issue:
17(24), P. 5863 - 5881
Published: Jan. 1, 2019
The
direct
C3-functionalization
of
quinoxalin-2(1H)-ones
via
C–H
bond
activation
has
recently
attracted
considerable
attention,
due
to
their
diverse
biological
activities
and
chemical
properties.
Chemical Science,
Journal Year:
2022,
Volume and Issue:
13(19), P. 5659 - 5666
Published: Jan. 1, 2022
General
photoactivation
of
EDA
complexes
between
arylsulfonium
salts
and
1,4-diazabicyclo[2.2.2]octane
was
discovered.
This
practical
mode
enables
the
generation
aryl
radicals
for
C–H
functionalization
arenes.
Angewandte Chemie International Edition,
Journal Year:
2019,
Volume and Issue:
58(44), P. 15803 - 15807
Published: Sept. 6, 2019
Abstract
An
enantioselective
three‐component
radical
reaction
of
quinolines
or
pyridines
with
enamides
and
α‐bromo
carbonyl
compounds
by
dual
photoredox
chiral
Brønsted
acid
catalysis
is
presented.
A
range
valuable
γ‐amino‐acid
derivatives
are
accessible
in
high
chemo‐,
regio‐,
enantioselectivity
from
simple,
readily
available
starting
materials
under
mild
conditions.
Using
the
same
strategy,
asymmetric
synthesis
1,2‐diamine
also
reported.
Green Chemistry,
Journal Year:
2019,
Volume and Issue:
21(23), P. 6241 - 6245
Published: Jan. 1, 2019
We
have
developed
a
metal-free
and
catalyst-free
visible-light-promoted
direct
C–H
sulfenylation
of
quinoxalin-2(1H)-ones
with
thiols
for
the
synthesis
diverse
3-sulfenylquinoxalin-2(1H)-ones.
Chemistry - A European Journal,
Journal Year:
2019,
Volume and Issue:
26(2), P. 369 - 373
Published: Oct. 9, 2019
A
practical
and
scalable
protocol
for
visible-light-accelerated
arylation
alkylation
of
quinoxalin-2(1H)-ones
with
hydrazines
is
reported.
In
this
protocol,
a
hydrazone-based
two-dimensional
covalent
organic
frameworks
(2D-COF-1)
was
employed
as
the
heterogeneous
photocatalyst
(PC).
Due
to
its
excellent
photocatalytic
properties,
good
chemical
stability
nature,
present
method
exhibits
high
efficiency,
functional
group
tolerance,
easy
scalability
remarkable
catalyst
reusability.
More
importantly,
it
provides
an
alternative
way
that
allows
rapid
access
various
C3
arylated
or
alkylated
in
greener
sustainable
manner.
Organic Letters,
Journal Year:
2018,
Volume and Issue:
20(17), P. 5497 - 5501
Published: Aug. 27, 2018
The
direct
synthesis
of
C(CF3)Me2-substituted
heteroarenes
by
decarboxylative
1,1-dimethyltrifluoroethylation
with
3,3,3-trifluoro-2,2-dimethylpropanoic
acid
is
reported.
This
method
does
not
need
the
transition-metal
catalyst,
and
base
crucial
for
this
reaction.
A
series
previously
unknown
C(CF3)Me2-containing
were
obtained
in
high
yields
have
potential
applications
drug
discovery
process.
