Highly efficient NHC-iridium-catalyzed β-methylation of alcohols with methanol at low catalyst loadings

Science China Chemistry, Journal Year: 2021, Volume and Issue: 64(8), P. 1361 - 1366

Published: June 17, 2021

Language: Английский

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Methanol as a greener C1 synthon under non-noble transition metal-catalyzed conditions

Coordination Chemistry Reviews, Journal Year: 2022, Volume and Issue: 475, P. 214851 - 214851

Published: Oct. 14, 2022

Language: Английский

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Highly Efficient Base Catalyzed N‐alkylation of Amines with Alcohols and β‐Alkylation of Secondary Alcohols with Primary Alcohols

ChemCatChem, Journal Year: 2023, Volume and Issue: 15(20)

Published: Aug. 8, 2023

Abstract Borrowing hydrogen (BH) reactions are very useful for the sustainable synthesis of C−C and C−N bonds. They generally operate with transition metal‐based catalysts along stoichiometric/catalytic amounts added base. Here we report that two catalytic transformations, carried out BH methodology, i. e. N ‐alkylation amines alcohols β‐alkylation secondary primary alcohols, can be performed effectively just base under air without using any catalyst. The mechanism is proposed to based on oxidation alcohol aldehyde followed by condensation an unsaturated intermediate which undergoes transfer hydrogenation product.

Language: Английский

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α-Methylation of Ketones and Indoles Catalyzed by a Manganese(I) PC_NHCP Pincer Complex with Methanol as a C₁ Source

Organometallics, Journal Year: 2022, Volume and Issue: 42(1), P. 62 - 71

Published: Dec. 28, 2022

Acceptorless alcohol dehydrogenation is a powerful reaction in sustainable synthesis. When combined tandem with dehydrogenative coupling or hydrogen borrowing, acceptorless can be used for the environmentally benign construction of C–C, C–N, and C–O bonds. While many these reactions rely on using precious metals, past decade use earth-abundant metals has become more prevalent. If green renewable feedstock could introduced as well, sustainability further increased. Methanol would such substrate serve C1 source when methylation wide variety substrates. Herein, we report efficient manganese-catalyzed α-methylation ketones indoles. The manganese catalyst based PCNHCP pincer platform containing rare central carbene donor. supports diverse set functional groups, occurs at moderate temperatures (110 °C), provides corresponding methylated indoles excellent yields. In contrast to previously reported mechanisms, herein mechanism does not depend metal–ligand cooperativity but rather proceeds via (i) metal-based featuring hydride (ii) ligand-centered where manganese-carbonyl acts catalytic center, depending additive.

Language: Английский

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NNN-Ru complexes catalyzed β-methylation of alcohols using methanol via borrowing hydrogen approach

Journal of Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 116026 - 116026

Published: Feb. 1, 2025

Language: Английский

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