Antibacterial and anti-inflammatory Bi-functional carbon dots hydrogel dressing for robust promotion of wound healing

Carbon, Journal Year: 2024, Volume and Issue: 226, P. 119202 - 119202

Published: April 28, 2024

Language: Английский

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Hydrogels and hydrogel-based drug delivery systems for promoting refractory wound healing: Applications and prospects

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 138098 - 138098

Published: Nov. 1, 2024

Language: Английский

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Nanocomposite sponge based on sodium alginate, polyvinyl alcohol, carbon dots, and woolly hedge nettle antibacterial extract for wound healing

Industrial Crops and Products, Journal Year: 2024, Volume and Issue: 214, P. 118554 - 118554

Published: April 12, 2024

Language: Английский

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Carbon dot based dressing for therapy of chemically-induced cutaneous burns

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: March 31, 2025

Chemical burns are a significant concern in Ukraine, with growing interest new treatments. Carbon-based nanoparticles, due to their anti-inflammatory, antioxidant, and antibacterial properties, have shown promise for wound healing. This study aimed evaluate the efficacy of carbon dots (CD) derived from citric acid urea promoting healing both acidic- alkali-induced rat model. The results indicated that acid-induced were slower heal exhibited more inflammation compared same initial injury level. Daily application CD dressings significantly reduced burn area during first week, i.e. accelerated process, although treatment was less effective burns. Both types led increased white blood cell counts, left shift, segmented neutrophils by day 7, signaling early acute inflammation. notably leukocytosis while preserving neutrophilia lymphocyte release on days 7 14. Furthermore, prevented post-burn anemia maintaining erythrocyte integrity. immune system's response levels consistent process skin histopathology.Overall, healing, particularly alkali burns, had systemic effect inflammatory responses.

Language: Английский

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Synergistic Enhancement of Targeted Wound Healing by Near-Infrared Photodynamic Therapy and Silver Metal–Organic Frameworks Combined with S- or N-Doped Carbon Dots

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(5), P. 671 - 671

Published: May 16, 2024

The literature data emphasize that nanoparticles might improve the beneficial effects of near-infrared light (NIR) on wound healing. This study investigates mechanisms synergistic healing potential NIR and silver metal–organic frameworks combined with nitrogen- sulfur-doped carbon dots (AgMOFsN-CDs AgMOFsS-CDs, respectively), which was conducted by testing fibroblasts viability, scratch assays, biochemical analysis, synchrotron-based Fourier transform infrared (SR-FTIR) cell spectroscopy imaging. Our findings reveal treatment AgMOFsN-CDs significantly increases viability to nearly 150% promotes proliferation, reduced interleukin-1 levels, suggesting an anti-inflammatory response. SR-FTIR shows this results in unique protein alterations, including increased α-helix structures cross-β. Additionally, synthesis enhanced upon treatment. likely mechanism behind observed changes is charge-specific interaction N-CDs from proteins, due nanocomposite’s optical characteristics. Remarkably, complete closure vitro assay achieved exclusively treatment, demonstrating promising application photodynamic therapy regenerative nanomedicine tissue engineering.

Language: Английский

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Harnessing the Therapeutic Potential of Carbon Dots for Efficient Wound Healing Management

BioNanoScience, Journal Year: 2024, Volume and Issue: 15(1)

Published: Dec. 21, 2024

Language: Английский

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Investigation of functional characteristics of copper/copper oxide nanoparticles synthesized with Moringa oleifera and Musa sps. extracts: in-vitro and porcine study

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Dec. 28, 2024

Language: Английский

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