Dyes and Pigments, Journal Year: 2025, Volume and Issue: unknown, P. 112789 - 112789
Published: March 1, 2025
Language: Английский
Dyes and Pigments, Journal Year: 2025, Volume and Issue: unknown, P. 112789 - 112789
Published: March 1, 2025
Language: Английский
Nano Materials Science, Journal Year: 2024, Volume and Issue: unknown
Published: July 1, 2024
Despite relevant advances, the pharmaceutical industry continues to strive with limited adaptability, moisture management, and discomfort caused by existing wound dressings. Adding these challenges are bioavailability pharmacokinetics of common (bio)therapeutics, overall leading unmet clinical demands, safety concerns, poor patient compliance. Ionogels, a versatile class materials comprising ionic liquids (ILs) confined in an organic or inorganic solid network, have been proposed overcome drawbacks. They demonstrated ability enhance antimicrobial mechanical properties resulting while allowing remarkable improvements drug solubility their delivery targeted sites. Nowadays, investigations trials still required fully leverage potential ionogels for human applications. However, recent FDA approval New Drug Application MRX-5LBT®, transdermal system, opens promising perspectives toward translation ionogels. This review focuses on advances achieved design applications, viz. topical formulations promote healing activity, as platforms improve (solubility bioavailability), at specific sites controlled release behaviour.
Language: Английский
Citations
6Analytica Chimica Acta, Journal Year: 2025, Volume and Issue: 1350, P. 343808 - 343808
Published: Feb. 16, 2025
Language: Английский
Citations
0ACS Biomaterials Science & Engineering, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 25, 2025
The rapid increase in the number of stimuli-responsive polymers, also known as smart has significantly advanced their applications various fields. These polymers can respond to multiple stimuli, such temperature, pH, solvent, ionic strength, light, and electrical magnetic fields, making them highly valuable both academic industrial sectors. Recent studies have focused on developing hydrogels with self-healing properties that autonomously recover structural integrity mechanical after damage. hydrogels, formed through dynamic covalent reactions, exhibit superior biocompatibility, responsiveness particularly pH changes. However, conventional are limited by weak brittle nature. To address this, ionizable moieties within polyelectrolytes be tuned create ionically cross-linked leveraging natural alginate, chitosan, hyaluronic acid, cellulose. integration liquids into these enhances conductivity, positioning significant agents. This review focuses emerging field ionic-based explores potential dermal tissue engineering.
Language: Английский
Citations
0Biomaterials, Journal Year: 2025, Volume and Issue: 320, P. 123234 - 123234
Published: March 4, 2025
Language: Английский
Citations
0Dyes and Pigments, Journal Year: 2025, Volume and Issue: unknown, P. 112789 - 112789
Published: March 1, 2025
Language: Английский
Citations
0