Materials Today Chemistry, Journal Year: 2024, Volume and Issue: 42, P. 102426 - 102426
Published: Dec. 1, 2024
Language: Английский
Materials Today Chemistry, Journal Year: 2024, Volume and Issue: 42, P. 102426 - 102426
Published: Dec. 1, 2024
Language: Английский
Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160550 - 160550
Published: Feb. 1, 2025
Language: Английский
Citations
1European Journal of Nuclear Medicine and Molecular Imaging, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 25, 2025
Enhancing therapeutic effectiveness is crucial for translating anticancer nanomedicines from laboratory to clinical settings. In this study, we have developed radioactive rhenium oxide nanoparticles encapsulated in human serum albumin ([188Re]ReOx-HSA NPs) concurrent radiotherapy (RT) and photothermal therapy (PTT), aiming optimize treatment outcomes. [188Re]ReOx-HSA NPs were synthesized by a controlled reduction of 188ReO4− HSA medium extensively characterized. The effect was demonstrated vitro murine melanoma (B16F10) cell line. vivo SPECT/CT imaging, autoradiography biodistribution studies performed after intratumoral injection tumor-bearing C57BL/6 mice. potential combined RT PTT also the aforesaid mice model. (size 4–6 nm) with high colloidal radiochemical stability. Upon laser (808 exposure on B16F10 cells incubated NPs, only < 20% alive demonstrating efficacy under Uniform dose distribution retention radiolabeled tumor volume observed via imaging studies. Tumor growth model significantly arrested ~ 1.85 MBq simultaneous irradiation, synergistic benefit PTT. These results demonstrate that intrinsically having unique features such as effects favorable nuclear decay characteristics RT/PTT, hold great promise translation.
Language: Английский
Citations
0Journal of Alloys and Compounds, Journal Year: 2025, Volume and Issue: unknown, P. 179390 - 179390
Published: Feb. 1, 2025
Language: Английский
Citations
0Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 527, P. 216382 - 216382
Published: Dec. 18, 2024
Language: Английский
Citations
1Published: Jan. 1, 2024
Language: Английский
Citations
0Materials Today Chemistry, Journal Year: 2024, Volume and Issue: 42, P. 102426 - 102426
Published: Dec. 1, 2024
Language: Английский
Citations
0