Biocomposite Polyvinyl Alcohol/Ferritin Hydrogels with Enhanced Stretchability and Conductivity for Flexible Strain Sensors

Gels, Journal Year: 2025, Volume and Issue: 11(1), P. 59 - 59

Published: Jan. 11, 2025

Protein-based hydrogels with stretchability and conductivity have potential applications in wearable electronic devices. However, the development of protein-based biocomposite is still limited. In this work, we used natural ferritin to develop a PVA/ferritin hydrogel by repetitive freeze–thaw method. hydrogel, ferritin, as nano spring, forms hydrogen bond PVA networks, which reduces crystallinity significantly improves hydrogel. The fracture strain 203%, stress 112.2 kPa. toughness enhanced 147.03 kJ/m3, more than 3 times that (39.17 kJ/m3). addition, free residues iron ions endow ionic (0.15 S/m). sensor constructed from shows good sensitivity (gauge factor = 1.7 at 150% strain), accurate real-time resistance response, long cyclic working stability when for joint motion monitoring. results indicate prepared facile method has flexible sensors. This work develops new preparation

Language: Английский

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Magnetic Polymeric Conduits in Biomedical Applications

Micromachines, Journal Year: 2025, Volume and Issue: 16(2), P. 174 - 174

Published: Jan. 31, 2025

Magnetic polymeric conduits are developing as revolutionary materials in regenerative medicine, providing exceptional benefits directing tissue healing, improving targeted medication administration, and facilitating remote control via external magnetic fields. The present article offers a thorough examination of current progress the design, construction, functionalization these hybrid systems. integration nanoparticles into matrices confers distinctive features, including regulated alignment, improved cellular motility, medicinal delivery, while preserving structural integrity. Moreover, incorporation multifunctional attributes, such electrical conductivity for cerebral stimulation optical characteristics real-time imaging, expands their range applications. Essential studies indicate that dimensions, morphology, surface chemistry, composition significantly affect biocompatibility, degrading characteristics, overall efficacy. Notwithstanding considerable advancements, issues concerning long-term biodegradability, scalability persist, addition to must uniform regulatory frameworks facilitate clinical translation. Progress additive manufacturing nanotechnology is overcoming obstacles, creation dynamic adaptive conduit structures designed particular biomedical requirements. conduits, by integrating usefulness safety, set transform therapies, presenting new avenue customized medicine advanced healthcare solutions.

Language: Английский

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Stimuli‐Responsive Core‐Shell Electrospun Nanofibers for Drug Delivery: A Mini‐Review

Journal of Applied Polymer Science, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 31, 2025

ABSTRACT Core‐shell nanofibers have the potential to surpass traditional monolithic electrospun in drug delivery, due their ability encapsulate sensitive therapeutics within core, protect them from degradation, and enable controlled release profiles through shell. When designed be stimuli‐responsive, these evolve “smart” delivery platforms for advanced therapeutic applications. This mini‐review examines recent advancements fabrication applications of stimuli‐responsive core‐shell nanofibers. Key techniques, such as coaxial electrospinning, single‐nozzle electrospinning using water‐in‐oil or oil‐in‐water emulsions immiscible blends (e.g., polyethylene oxide chitosan; polyvinylpyrrolidone polyvinylidene), needleless post‐fabrication coating methods, are discussed along with respective advantages limitations. Additionally, review also explores how can engineered respond stimuli like near‐infrared (NIR) light, ultrasound, temperature, pH changes. Representative examples illustrate reduce initial burst release, on‐demand chemodrug implement photothermal therapy against cancer cells. At end, we offer perspectives on challenges, opportunities, new directions future development.

Language: Английский

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Magnetic Ionogel and Its Applications

Gels, Journal Year: 2025, Volume and Issue: 11(4), P. 219 - 219

Published: March 21, 2025

Magnetic ionogels, a category of hybrid materials consisting magnetic nanoparticles and ionic liquids, have garnered significant interest owing to their remarkable attributes, including tunability, flexibility, reactivity external fields. These provide distinctive amalgamation the benefits both resulting in improved efficacy across many applications. ionogels may be readily controlled using fields, rendering them suitable for drug administration, biosensing, soft robotics, actuators. The capacity incorporate these into dynamic systems presents novel opportunities development responsive, intelligent capable real-time environmental adaptation. Nonetheless, despite promising potential problems persist, optimization particle dispersion, enhancement ionogel mechanical strength, improvement long-term stability. This review comprehensive examination syntheses, characteristics, uses emphasizing breakthroughs persistent within domain. We examine recent advancements prospective research trajectories aimed at enhancing design practical applications diverse biomedical uses, sensors, next-generation seeks elucidate present status influence on science engineering.

Language: Английский

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Three-Dimensional Printing for Accessible and Personalized Ophthalmic Care: A Review

Journal of Clinical & Translational Ophthalmology, Journal Year: 2025, Volume and Issue: 3(2), P. 6 - 6

Published: March 26, 2025

Over 2.2 billion people across the globe face significant barriers to accessing essential ophthalmic care, with elderly, rural, and refugee populations being disproportionately affected, deepening existing disparities in eye care. Three-dimensional printing is a novel technology that has potential transform field improve access by alleviating many patient-specific barriers. This article delves into evolution of 3D within ophthalmology, highlighting its current applications future potential. It explores various techniques numerous biomaterials discussing their effectiveness creating advanced solutions such as bioengineered corneas, ocular prosthetics, innovative treatments for dry syndrome, from punctal plugs lacrimal gland models. Additionally, revolutionized drug delivery systems conditions like glaucoma, retinal diseases, brachytherapy. Whether through printed contact lens-based or polycaprolactone implants biodegrade provide sustained release without adverse effects, these hold immense field. Despite promise, integration clinical practice presents challenges, which addresses alongside strategies overcoming them. By mapping out technological advancements this review offers roadmap enhancing global care accessibility improving patient outcomes on scale.

Language: Английский

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Interface conditions for a polyelectrolyte gel in a salt solution with a thin electrical double layer

Proceedings of the Royal Society A Mathematical Physical and Engineering Sciences, Journal Year: 2025, Volume and Issue: 481(2306)

Published: Jan. 1, 2025

Polyelectrolyte gels are electro-active soft materials that often surrounded by a viscous salt solution. The formation of an electrical double layer (EDL) at the interface between gel and solution can give rise to fluid-structure interactions driven Coulomb forces. However, these usually neglected in modelling studies due difficulty resolving EDL, which has thickness is orders magnitude smaller than characteristic size. In this paper, asymptotically consistent model polyelectrolyte derived thin-EDL limit. consists bulk equations describing electrically neutral bath, along with interfacial conditions capture electro-mechanical impact EDL. A key result derivation Helmholtz–Smoluchowski slip condition describes how shear stresses EDL lead flow surrounding on gel-gel friction swelling-driven instabilities discussed. here will better understanding interact external solution, crucial for applications.

Language: Английский

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3D Printing of High Strength Thermally Stable Sustainable Lightweight Corrosion-Resistant Nanocomposite by Solvent Exchange Postprocessing

ACS Sustainable Chemistry & Engineering, Journal Year: 2024, Volume and Issue: 13(1), P. 423 - 435

Published: Dec. 18, 2024

3D printing of cellulose acetate (CA)-based, sustainable, thermally stable nanocomposites is challenging due to their fast drying, nozzle clogging, and complex rheological behavior. In this study, we developed an extrusion-printable ink based on CA nanocrystals (CNCs) using a trisolvent wet blending method, followed by postprinting pore-inducing processing technique. The performed well in both tensile- compression-based mechanical tests. Moreover, the demonstrated malleable deformation during compression testing without any premature fracture, unlike commercial commodity plastics. thermal stability was assessed thermogravimetric analysis, showing ∼ 28 °C improvement onset degradation temperature after addition 5 wt % CNCs. Solvent tolerance tests against various solvents indicated excellent solvent resistance. lightweight showed no deterioration, even long-term exposure water vapor. Finally, anticorrosion behavior samples evaluated as coating material for metal (Al), demonstrating protection corrosive acid vapors. Thus, application 3D-printed exhibits significant promise implementation fields lightweight, anticorrosive engineering materials.

Language: Английский

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