Zinc Oxide Nanoparticle Loaded L-Carnosine Biofunctionalized Polyacrylonitrile Nanofibrous Wound Dressing for Post-Surgical Treatment of Melanoma
Polymers,
Journal Year:
2025,
Volume and Issue:
17(2), P. 173 - 173
Published: Jan. 12, 2025
Nanofibrous
dressing
materials
with
an
antitumor
function
can
potentially
inhibit
recurrence
of
melanoma
following
the
surgical
excision
skin
tumors.
In
this
study,
hydrolyzed
polyacrylonitrile
(hPAN)
nanofibers
biofunctionalized
L-carnosine
(CAR)
and
loaded
bio
(CAR)-synthesized
zinc
oxide
(ZnO)
nanoparticles,
ZnO/CAR-hPAN
(hereafter
called
ZCPAN),
were
employed
to
develop
antimelanoma
wound
dressing.
Inspired
by
formulation
commercial
healing
Zn-CAR
complex,
i.e.,
polaprezinc
(PLZ),
for
first
time,
we
benefitted
from
synergy
CAR
create
nanofibrous
According
scanning
electron
microscopy
(SEM)
images,
ultrafine
ZnO
nanoparticles
homogenously
distributed
throughout
The
ZCPAN
nanofiber
mat
showed
a
significantly
higher
toughness
(18.7
MJ.m−3
vs.
1.4
MJ.m−3)
enhanced
elongation
at
break
(stretchability)
compared
neat
PAN
(12%
9.5%).
Additionally,
optical
coherence
elastography
(OCE)
measurements
indicated
that
was
as
stiff
50.57
±
8.17
kPa
which
is
notably
larger
than
dressing,
24.49
6.83
kPa.
optimum
mechanical
performance
originates
physicochemical
interaction
ligands,
hPAN
nanofibers,
through
hydrogen
bonding,
electrostatic
esterification,
verified
using
ATR-FTIR.
An
in
vitro
cell
viability
assay
human
cells
implied
are
killed
presence
nanofibers.
Thanks
ROS
generating
behavior
high
reactive
oxygen
species
(ROS)-induced
oxidative
damage
cells,
CellROX
assay.
regard,
apoptotic
response
recorded
apoptosis
Taken
together,
induce
effect
stress
thus
potential
material
suppress
regrowth
after
Language: Английский
Development and Characterization of Farnesol Complexed in β- and Hydroxypropyl-β-cyclodextrin and their Antibacterial Activity
Carbohydrate Research,
Journal Year:
2025,
Volume and Issue:
550, P. 109406 - 109406
Published: Jan. 23, 2025
Language: Английский
Conversion of VOC-derived CO2 into sustainable products with a natural magnetic alginate composite
Erika Saccullo,
No information about this author
Vincenzo Patamia,
No information about this author
Alessandra Bifarella
No information about this author
et al.
International Journal of Biological Macromolecules,
Journal Year:
2025,
Volume and Issue:
unknown, P. 140695 - 140695
Published: Feb. 1, 2025
Language: Английский
Natural antenna molecule in halloysite-kojic acid composite for the solar photocatalytic CO2 methanation
Erika Saccullo,
No information about this author
Giusy Dativo,
No information about this author
Rosamaria Lombardo
No information about this author
et al.
Materials Today Chemistry,
Journal Year:
2025,
Volume and Issue:
44, P. 102587 - 102587
Published: Feb. 12, 2025
Language: Английский
Advances in polysaccharide‐based materials for biomedical and pharmaceutical applications: A comprehensive review
Jiahao Li,
No information about this author
Hanan Hassan Ahmed,
No information about this author
Ali M. Hussein
No information about this author
et al.
Archiv der Pharmazie,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 9, 2024
Polysaccharides,
the
most
abundant
biopolymers
in
nature,
have
attracted
attention
of
researchers
and
clinicians
due
to
its
practicality
biomedical
pharmaceutical
sciences.
These
biomaterials
high
bioavailability
play
structural
functional
roles
living
organisms.
Polysaccharides
are
classified
into
several
groups
based
on
their
origin,
including
plant
polysaccharides
marine
(like
chitosan,
hyaluronic
acid,
dextran,
alginates,
etc.)
with
specific
applications.
possess
unique
physicochemical
(such
as
surface
groups,
solubility,
stability),
mechanical
strength
tensile),
antioxidant
activity,
biocompatibility,
biodegradability,
renewability,
non-immunogenicity)
characteristics
which
made
them
excellent
platforms
for
a
wide
variety
Ease
extraction
different
preparation
approaches
mentioned
other
potential
properties
that
further
improved
They
drug/bioactive
encapsulation
capacity
sustained/controlled
release
manner
vivo
microenvironments.
The
anti-inflammatory
immunomodulation,
stimuli-responsive
release,
passive
active
delivery
considered
features
these
indicated
practical
applications
sciences,
biosensors,
tissue
engineering,
implantation,
wound
healing,
vascular
grafting,
vaccines.
This
review
highlights
advances
polysaccharide-based
materials
Language: Английский
Unveiling the chemistry of antibody conjugation for enhanced PET imaging: Current trends and future directions
Erika Saccullo,
No information about this author
Vincenzo Patamia,
No information about this author
Elisabetta Grazia Tomarchio
No information about this author
et al.
Bioorganic Chemistry,
Journal Year:
2024,
Volume and Issue:
155, P. 108115 - 108115
Published: Dec. 31, 2024
Language: Английский
Learning Strategies from Nature’s Blueprint to Cyclic Carbonate Synthesis
Erika Saccullo,
No information about this author
Vincenzo Patamia,
No information about this author
Chiara Zagni
No information about this author
et al.
ChemSusChem,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 23, 2024
Abstract
Nature
is
a
remarkable
source
of
inspiration
for
developing
sustainable
and
eco‐friendly
synthetic
procedures.
In
recent
years,
the
synthesis
cyclic
carbonates
has
garnered
significant
attention
due
to
their
versatile
applications
in
various
fields,
including
materials
science,
pharmaceuticals,
green
chemistry.
Drawing
from
nature,
researchers
have
explored
innovative
routes
that
mimic
biological
processes
produce
efficiently
sustainably.
This
article
reviews
nature‐inspired
procedures
carbonate
formation,
highlighting
key
strategies
principles
employed.
Through
biomimicry,
aim
harness
efficiency
selectivity
observed
systems
develop
greener
more
methods
synthesis.
Integrating
bio‐inspired
offers
opportunities
improving
contributes
reducing
environmental
impact
associated
with
traditional
chemical
processes.
review
underscores
potential
approaches
advancing
field
toward
environmentally
benign
practices,
focusing
on
literature.
Language: Английский