Portable Thiocholine-Based Sensor for Monitoring Blood Cholinesterase Activity and Detecting Organophosphate and Carbamate Pesticides Using Personal Glucose Meters

Foods, Journal Year: 2025, Volume and Issue: 14(7), P. 1136 - 1136

Published: March 25, 2025

The widespread use of organophosphate and carbamate pesticides in agriculture poses significant health risks due to their cholinesterase (ChE) inhibitory effects. However, existing detection methods are often expensive require specialized facilities, limiting accessibility. This study developed a cost-effective, portable, sensitive sensor using personal glucose meter (PGM) technology detect ChE activity human blood pesticide residues vegetables. A thiocholine-based assay was designed measure via PGM, enabling the assessment enzyme inhibition caused by exposure. optimized PGM-based achieved limits (LODs) 0.138 ppm for mevinphos 0.113 carbofuran standard solutions, with strong correlations (R > 0.99) between fortified samples, indicating high sensitivity accuracy. method demonstrated reliable at concentrations as low 0.05 ppm. offers portable efficient tool point-of-care diagnostics, environmental monitoring, food safety applications. approach enhances public protection accessible detection. Future work will focus on expanding capabilities, improving specificity stability, conducting clinical validation broader

Language: Английский

An acylaminoacyl-peptide hydrolase-activated fluorescent probe for ultrasensitive detection of pesticide residue

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2025, Volume and Issue: unknown, P. 126152 - 126152

Published: April 1, 2025

Language: Английский

Effect of structure on sensing performance of nitro explosives with high sensitivity and mechanism of two Tb(III) coordination polymers

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2024, Volume and Issue: 324, P. 124943 - 124943

Published: Aug. 10, 2024

Language: Английский