Restorative Dental Resin Functionalized with Calcium Methacrylate with a Hydroxyapatite Remineralization Capacity DOI Creative Commons
Xin Zhang, Yuxuan Zhang, Ying Li

et al.

Materials, Journal Year: 2023, Volume and Issue: 16(19), P. 6497 - 6497

Published: Sept. 29, 2023

The ability of dental materials to induce the mineralization enamel like hydroxyapatite (HA) is great importance. In this article, a novel kind restorative material characterized by was fabricated photopolymerization. Calcium methacrylate (CMA) introduced into classical bisphenol A-glycidyl (Bis-GMA) and triethylene glycol dimethacrylate (TEGDMA) resin formulation. This functional (BTCM) calcium-rich can be prepared simply one-step influence CMA on photopolymerization kinetics, resin's mechanical properties, its capacity dynamic in situ HA were examined. Real-time FTIR, compression modulus, scanning electron microscopy, X-ray spectroscopy, MTT assay, cell attachment test carried out. obtained data analyzed for statistical significance using analysis variance (ANOVA). Double bond conversion could completed less than 300 s, while modulus BTCM decreased with increase content (30 wt%, 40 50 wt%). After being soaked Ca(NO3)2 Na2HPO4 solutions alternatively, dense crystals found surface which contained CMA. amount increased content. results indicated that possesses good biocompatibility, adhesion proliferation investigation demonstrated L929 cells adhere proliferate well BTM. Thus, our approach provides straightforward, cost-effective, environmentally friendly solution has potential immediate clinical use.

Language: Английский

The DIAD Approach to Correlative Synchrotron X-ray Imaging and Diffraction Analysis of Human Enamel DOI Creative Commons
Cyril Besnard,

Ali Marie,

Sisini Sasidharan

et al.

Chemical & Biomedical Imaging, Journal Year: 2024, Volume and Issue: 2(3), P. 222 - 232

Published: March 8, 2024

The Dual Imaging and Diffraction (DIAD) beamline at Diamond Light Source (Didcot, U.K.) implements a correlative approach to the dynamic study of materials based on concurrent analysis identical sample locations using complementary X-ray modalities reveal structural detail various length scales. Namely, underlying principle its practical implementation allow collocation chosen regions within their interrogation real-space imaging (radiography tomography) reciprocal space scattering (diffraction). switching between two principal modes is made smooth rapid by design, so that data collected interlaced obtain near-simultaneous multimodal characterization. Different specific photon energies are used for each mode, interlacing acquisition steps allows conducting static experiments. Building demonstrated realization this state-of-the-art requires further refining experimental practice, namely, methods gauge volume under different beam–sample interaction. To address challenge, experiments were conducted DIAD devoted human dental enamel, hierarchical structure composed hydroxyapatite mineral nanocrystals, as previously affected caries (tooth decay) well conditions simulating process acid demineralization. Collocation correlation achieved WAXS (wide-angle scattering), 2D (radiographic), 3D (tomographic) imaging. While in or reveals details microstructure, provided statistical nanoscale ultrastructural polycrystal reciprocal-space information such phase preferred orientation (texture). Careful registration positions recorded during scans allowed direct covisualization from modalities. volumes identified visualized tomographic sets, revealing local support interpretation diffraction patterns. present 4D microscopy paradigm following progression demineralization with time-dependent pattern evolution an transferable other material systems.

Language: Английский

Citations

2
Advanced Time-Stepping Interpretation of Fly-Scan Continuous Rotation Synchrotron Tomography of Dental Enamel Demineralization DOI Creative Commons
Cyril Besnard,

Ali Marie,

Sisini Sasidharan

et al.

Chemical & Biomedical Imaging, Journal Year: 2024, Volume and Issue: 2(3), P. 213 - 221

Published: Feb. 8, 2024

High-resolution spatial and temporal analysis 3D visualization of time-dependent processes, such as human dental enamel acid demineralization, often present a challenging task. Overcoming this challenge requires the development special methods. Dental caries remains one most important oral diseases that involves demineralization hard tissues consequence production by bacteria. Enamel has hierarchically organized architecture extends down to nanostructural level high resolution study its evolution in detail. is dynamic process best investigated with help situ experiments. In previous studies, synchrotron tomography was applied structure at certain time points (time-lapse tomography). Here, another distinct approach time-evolving studies presented, whereby sample image reconstructed it undergoes continuous rotation over virtually unlimited angular range. The resulting (single) data set contains for multiple (potentially overlapping) intermediate tomograms can be extracted analyzed desired using time-stepping selection subsets from fly-scan recording. One advantages reduces amount required collect an equivalent number single tomograms. Another advantage nominal step between successive reconstructions significantly reduced. We acidic observed progression steps smaller than total acquisition tomogram, voxel size 0.5 μm. It expected presented paper useful high-resolution other processes assessing small structural modifications evolving hierarchical materials.

Language: Английский

Citations

1
The application of hydrogels for enamel remineralization DOI Creative Commons

Jiayi Liao,

Junhong Qiu,

Yanjun Lin

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(13), P. e33574 - e33574

Published: June 25, 2024

Enamel is composed of numerous uniformly wide, well-oriented hydroxyapatite crystals. It possesses an acellular structure that cannot be repaired after undergoing damage. Therefore, remineralization enamel defects has become a focal point research. Hydrogels, which are materials with three-dimensional structures derived from cross-linking polymers, have garnered significant attention in recent studies. Their exceptional properties make them valuable the application remineralization. In this review, we summarize and formation enamel, present design considerations hydrogels for remineralization, explore diverse types context, finally, shed light on potential future applications field.

Language: Английский

Citations

1
Identification of chemical transformations in enamel apatite during the development of fissure caries at the nanoscale by means of synchrotron infrared nanospectroscopy: A pilot study DOI
П. В. Середин, D. L. Goloshchapov, Yaroslav A. Peshkov

et al.

Nano-Structures & Nano-Objects, Journal Year: 2024, Volume and Issue: 38, P. 101205 - 101205

Published: May 1, 2024

Language: Английский

Citations

1
Restorative Dental Resin Functionalized with Calcium Methacrylate with a Hydroxyapatite Remineralization Capacity DOI Creative Commons
Xin Zhang, Yuxuan Zhang, Ying Li

et al.

Materials, Journal Year: 2023, Volume and Issue: 16(19), P. 6497 - 6497

Published: Sept. 29, 2023

The ability of dental materials to induce the mineralization enamel like hydroxyapatite (HA) is great importance. In this article, a novel kind restorative material characterized by was fabricated photopolymerization. Calcium methacrylate (CMA) introduced into classical bisphenol A-glycidyl (Bis-GMA) and triethylene glycol dimethacrylate (TEGDMA) resin formulation. This functional (BTCM) calcium-rich can be prepared simply one-step influence CMA on photopolymerization kinetics, resin's mechanical properties, its capacity dynamic in situ HA were examined. Real-time FTIR, compression modulus, scanning electron microscopy, X-ray spectroscopy, MTT assay, cell attachment test carried out. obtained data analyzed for statistical significance using analysis variance (ANOVA). Double bond conversion could completed less than 300 s, while modulus BTCM decreased with increase content (30 wt%, 40 50 wt%). After being soaked Ca(NO3)2 Na2HPO4 solutions alternatively, dense crystals found surface which contained CMA. amount increased content. results indicated that possesses good biocompatibility, adhesion proliferation investigation demonstrated L929 cells adhere proliferate well BTM. Thus, our approach provides straightforward, cost-effective, environmentally friendly solution has potential immediate clinical use.

Language: Английский

Citations

1